@article{article_492329, title={Evaluation of the chemical composition and biological activities of Salvia officinalis subsp. lavandulifolia (Vahl) Gams essential oil}, journal={Natural Volatiles and Essential Oils}, volume={5}, pages={1–6}, year={2018}, author={Öztürk, Gözde and Demirci, Betül and Demirci, Fatih}, keywords={Salvia lavandulifolia Vahl.,essential oil,antibacterial activity,antioxidant}, abstract={<p style="text-align:justify;"> <span lang="en-gb" style="font-size:11pt;line-height:107%;font-family:Calibri, sans-serif;" xml:lang="en-gb">The main aim of the present study was to
investigate the antibacterial effect of the commercial Pharma Grade <i>Salvia lavandulifolia </i> Vahl. (Lamiaceae)
essential oil against the skin pathogen <i>
Staphylococcus aureus </i>. The chemical composition of the essential oil was
confirmed by GC and GC/MS, simultaneously. Camphor (30.5%), 1,8-cineole
(24.8%), <i>α </i>-pinene (6.5%), linalool
(4.0%) and linalyl acetate (3.5%) were found as major components, respectively.
The bioactivity of the essential oil and its main compounds were tested using
the <i>in vitro </i> microdilution technique.
Minimum inhibitory concentration (MIC) values of <i>α </i>-pinene, essential oil, camphor, linalool and linalyl acetate were
in the range of 2.5-10 mg/mL, respectively. The results showed that the tested
pathogen was only moderately susceptible against the essential oil and its main
compounds when compared with standard antibiotics. In addition, the <i>in vitro </i> antioxidant activity was
evaluated using the radical scavenging activity mediated by
1,1-diphenyl-2-picrylhydrazyl (DPPH). The activity range was found more than 30
mg/mL for all tested oil samples, compared with the standard. The results
suggested that the oil and its major constituents were rather weak
antimicrobial agent supporting its antiseptic folk medicinal use. </span> <br /> </p>}, number={3}, publisher={Badebio Biotechnology Ltd.}