TY  - JOUR
T1  - Yetiştiriciliği Yapılan Mersin Balıklarından İzole Edilen Bakterilerin Antimikrobiyal Direnç Profillerinin Belirlenmesi
TT  - Determination of Antimicrobial Resistance Profiles of the Bacteria Isolated from Cultured Sturgeons
AU  - Terzi, Ertuğrul
PY  - 2018
DA  - December
Y2  - 2018
JF  - Memba Kastamonu Üniversitesi Su Ürünleri Fakültesi Dergisi
PB  - Kastamonu University
WT  - DergiPark
SN  - 2147-2254
SP  - 7
EP  - 13
VL  - 4
IS  - 2
LA  - tr
AB  - Türkiye'de mersin balıklarıyetiştiriciliği son yıllarda artmaya başlamıştır. Balıklar yetiştiricilikaşamasında çeşitli hastalıklara maruz kalır ve bu hastalıklar ekonomikkayıplara sebep olabilmektedir. Bu çalışmada karaca (Acipensergueldenstaedtii) ve sibirya (Acipenser baerii) mersin balıklarındanortalama ağırlıkları 3 kg’a ulaşıncaya kadar geçen sürede izole edilen toplam37 suşun antimikrobiyal maddelere karşı direnç profilleri ve direnç genlerinvarlığı araştırılmıştır. Bakterilerin en fazla dirençli olduklarıantibiyotikler sulfametoksazol ve ampisilin olarak tespit edilmiştir (%97.3).Bunun yanında bakterilerin test edilen antibiyotikler arasında gentamisin,oksolinik asit, trimetoprim+sulfametoksazol ve florfenikole karşıhassasiyetleri sırasıyla %86.5, %59.5, %45.9 ve %40.5 olarak tespit edilmiştir.Bakterilerde taranan genlerden tetA ve tetB genleri sırasıyla %10.8 ve 21.6 olarak tespit edilmiştir. En fazla tespit edilen genler % 24oranla ampC ve cmlA genleri olmuştur. Bu genleri % 19’luk oranla sul3 ve floR genleritakip etmiştir. Gerçekleştirilen bu çalışmada,bakterilerin antibiyotiklere karşı direnç seviyelerinin oksitetrasiklin,streptomisin, enrofloksasin ve ampisilinde %50’den yüksek olması, mersin balığıyetiştiriciliğinde bakteriyel hastalıkların tedavisinde gelecekte sorunlaryaşanacağını söylenebilir.
KW  - Antimikrobiyal
KW  - Antibiyogram
KW  - Direnç genleri
KW  - Mersin Balığı
N2  - Sturgeon farming in Turkey has increased in recent years. Fish areexposed to various diseases during the culturing period and these diseases cancause economic losses. In this study, a total of 37 strains isolated fromdiamond (Acipenser gueldenstaedtii) and siberian (Acipenser baerii)sturgeons till their average weights reach up to 3 kg were used to determineresistance profiles against antimicrobial substances and investigated theirresistance genes. The most resistance to antibiotics in bacteria were found assulphamethoxazole and ampicillin (97.3%). Moreover, the susceptibility ofbacteria to the tested antibiotics for gentamicin, oxolinic acid, trimethoprim+ sulfamethoxazole and florfenicol was determined as 86.5%, 59.5%, 45.9% and40.5%, respectively. tetA ve tetB genes in the tested bacteria were detected as 10.8% and 21.6%,respectively. The most common genes were ampC and cmlAgenes (24%) followed by sul3 and floR genes with a ratio of 19%.In this study, it can be said that there may be problems in the treatment ofbacterial diseases in sturgeon farming because of being higher than 50% of theresistance levels of bacteria against antibiotics such as oxytetracycline,streptomycin, enrofloxacin and ampicillin.
CR  - Agersø, Y., Bruun, M.S., Dalsgaard, I., Larsen, J.L., 2007. The tetracycline resistance gene tet(E) is frequently occurring and present on large horizontally transferable plasmids in Aeromonas spp. from fish farms, Aquaculture, 266: 47-52. https://doi.org/10.1016/j.aquaculture.2007.01.012
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CR  - Boran, H., Terzi, E., Altinok, I., Capkin, E., Bascinar, N., 2013. Bacterial diseases of cultured mediterranean horse mackerel (Trachurus mediterraneus) in sea cages. Aquaculture, 396: 8-13. https://doi.org/10.1016/j.aquaculture.2013.02.025
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CR  - Kayiş, Ş., Er, A., Kangel, P., Kurtoğlu, İ.Z., 2017. Bacterial pathogens and health problems of Acipenser gueldenstaedtii and Acipenser baerii sturgeons reared in the Eastern Black Sea region of Turkey. Iranian Journal of Veterinary Research, 18(1): 18-24.
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CR  - TUIK, 2018. Türkiye İstatistik Kurumu 2017 Veri Seti, Su Ürünleri İstatistikleri, Ankara
UR  - https://dergipark.org.tr/en/pub/menba/issue//492888
L1  - https://dergipark.org.tr/en/download/article-file/610227
ER  -