TY  - JOUR
T1  - Single Dose Methotrexate in Treatment of Ectopic Pregnancy: Review of 32 Case
TT  - Single Dose Methotrexate in Treatment of Ectopic Pregnancy: Review of 32 Case
AU  - Aybatlı, Aysun
AU  - Kaptan, Petek Balkanlı
AU  - Sayın, Niyazi Cenk
AU  - Alicik, Mehmet
AU  - Yüce, Mehmet Ali
PY  - 2011
DA  - January
DO  - 10.5174/tutfd.2009.02161.1
JF  - Balkan Medical Journal
PB  - Trakya University
WT  - DergiPark
SN  - 2146-3123
SP  - 10
EP  - 13
VL  - 2011
IS  - 1
LA  - en
AB  - Objective: To evaluate the efficacy of single dose intramuscular methotrexate in the treatment of ectopic pregnancy.         Material and Methods: 32 patients who matched the inclusion criteria were enrolled. Success of treatment was defined as a resolution of ectopic pregnancy without performing surgical intervention. The cases in whom the treatment was successful and those that were not were compared for β-hCG values and clinical features.         Results: β-hCG at diagnosis averaged 1293.9 mIU/ml. Of the 32 patients who received methotrexate, 26 were successfully treated. 23 patients (71.8%) received a single dose of methotrexate, 3 patients (9.3%) received an additional dose of methotrexate, 6 patients (18.7%) who had failed methotrexate required surgery for cure. The success rate of single-dose methotrexate was 79.3%.         Conclusion: Our study shows that single dose systemic methotrexate treatment can be used as an option in unruptured pregnancies.
KW  - Ectopic pregnancy
KW  - methotrexate
KW  - β-hCG
KW  - single dose
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UR  - https://doi.org/10.5174/tutfd.2009.02161.1
L1  - https://dergipark.org.tr/en/download/article-file/42818
ER  -