@article{article_508406, title={A Rare Cause of Rhabdomiyolysis:Sildenafil}, journal={Journal of Emergency Medicine Case Reports}, volume={10}, pages={98–100}, year={2019}, DOI={10.33706/jemcr.508406}, author={Şimşek, Selma and İhtiyar, Büşra and Akça, Hatice Şeyma and Kokulu, Kamil and Eroğlu, Serkan Emre}, keywords={rhabdomiyolysis,Sildenafil}, abstract={<p class="Gvde" style="text-align:justify;line-height:150%;"> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us">INTRODUCTION </span> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us"> </span> </p> <p> </p> <p class="Gvde" style="text-align:justify;line-height:150%;"> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us"> </span> </p> <p>  </p> <p class="MsoNormal" style="line-height:150%;"> <span lang="en-us" style="color:rgb(33,33,33);" xml:lang="en-us">Rhabdomyolysis is a syndrome characterized by muscle necrosis
and the release of </span> <span lang="it" style="color:rgb(33,33,33);" xml:lang="it">intracellular muscle components </span> <span lang="en-us" style="color:rgb(33,33,33);" xml:lang="en-us"> into the bloodstream. </span> </p> <p> </p> <p class="MsoNormal" style="line-height:150%;"> <span lang="en-us" style="color:rgb(33,33,33);" xml:lang="en-us"> </span> </p> <p>  </p> <p class="Gvde" style="text-align:justify;line-height:150%;"> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us">CASE
REPORT </span> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us"> </span> </p> <p> </p> <p class="Gvde" style="text-align:justify;line-height:150%;"> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us"> </span> </p> <p>  </p> <p class="Gvde" style="text-align:justify;line-height:150%;"> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us">A
29-year-old male patient presented to the emergency department complaining of
nausea, vomiting and widespread body pain. Physical examination of the agitated
patient who did not want to talk was as followed; Vitals: BP: 115/50, Pulse:
85, Sa02: 95. The patient was conscious, oriented </span> <span lang="pt" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="pt">, cooper </span> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us">ative and his GCS was 15. Biochemical values
​​in laboratory tests; AST: 224, ALT: 183, LDH: 1273, CK: 33639, and drawn
arterial blood gas were determined as follows: pH: 7.45, hHCO3:18.7, lactate:
2.4. All other laboratory tests were normal. An ECG was performed and it showed
sinus tachycardia. When anamnesis was deepened, he stated that he used S </span> <span lang="nl" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="nl">ildenafil </span> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us">and alcohol 24 hours
before and just 3 hours before his admission to the hospital. Patient informed
us that there was no coitus. In the follow-up, the patient who was given
hydration and sodium bicarbonate treatment did not develop dialysis necessity,
his biochemical values ​​showed a rapid decrease of CK level 24000-11000-5000
and the patient was discharged because of the decline of all  his complaints. </span> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us"> </span> </p> <p> </p> <pre style="text-align:justify;line-height:150%;background:#FFFFFF;"> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us">DISCUSSION </span> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us"> </span> </pre> <p> </p> <p class="Gvde" style="text-align:justify;line-height:150%;"> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us"> <br /> </span> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us">Rhabdomyolysis is a syndrome characterized by
muscle necrosis and the release of </span> <span lang="it" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="it">intracellular muscle components </span> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us"> into the
bloodstream. The true incidence of Sildenafil-related renal matters is unknown,
since the post-marketing data are very limited. More cases can be detected as
the number of prescription of Sildenafil increases. </span> <span lang="en-us" style="font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us"> </span> </p> <p> </p> <p class="MsoNormal" style="line-height:150%;"> <span lang="en-us" style="color:rgb(33,33,33);" xml:lang="en-us"> </span> </p> <p>  </p> <pre style="text-align:justify;line-height:150%;background:#FFFFFF;"> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;color:rgb(33,33,33);" xml:lang="en-us"> </span> </pre> <p>  </p> <pre style="te}, number={4}, publisher={Acil Tıp Uzmanları Derneği}