TY  - JOUR
T1  - Investigation of Oxidative Stress in Van Fish (Alburnus tarichi Guldenstadt, 1814) During Reproductive Migration
TT  - Van Balığında (Alburnus tarichi Guldenstadt, 1814) Üreme Göçü Sırasında Oksidatif Stresin Araştırılması
AU  - Oğuz, Ahmet Regaib
AU  - Özok, Necati
AU  - Omar, Aso
AU  - Alkan, Zehra
AU  - Kıraççakalı, Ayşe Nur
PY  - 2019
DA  - March
Y2  - 2019
DO  - 10.17798/bitlisfen.512275
JF  - Bitlis Eren Üniversitesi Fen Bilimleri Dergisi
PB  - Bitlis Eren University
WT  - DergiPark
SN  - 2147-3129
SP  - 90
EP  - 97
VL  - 8
IS  - 1
LA  - en
AB  - Van Fish is an anadromous species of endemic toTurkey's largest lake. The fish migrate to the freshwater pouring from thealkaline Lake Van to the lake for the reproduction every year. Fish are exposedto different stress factors such as fasting, salt and pH adaptation duringmigration. In this study, total oxidant and antioxidant, lipid peroxidation andDNA damages in tissues such as gill, liver, plasma, brain and muscle werecompared before and after reproductive migration. Total oxidant status (TOS) ofthe fish caught in the lake before reproduction, liver and kidney tissues,total antioxidant status (TAS), fish liver caught from freshwater, fish fromthe lake were observed to be high in the brain and kidney tissues (P <0.05).Malondialdehyde (MDA) levels were found to be higher in the liver and kidney ofthe fish sampled from the freshwater and lake, respectively. (P <0.05). DNAdamage was found only in the liver of fish sampled from freshwater. As a result,the reactions of the organs against stress effects encountered duringreproduction migration were determined.
KW  - Van Fish
KW  - Oxidative stress
KW  - Lipid peroxidation
KW  - DNA damage
N2  - Van Balığı, Türkiye’nin en büyük gölüneendemik anadrom bir türdür. Balıklar, her sene üremesini gerçekleştirmek içinalkalin Van Gölünden göle dökülen tatlı sulara göç ederler. Balık bu göçsırasında açlık, tuz ve pH adaptasyonu gibi farklı stres faktörlerine maruzkalır. Bu çalışmada, Van Balığının üreme göçü öncesi ve sonrasında plazma, solungaç,karaciğer, beyin ve kas gibi dokularindaki total oksidan ve antioksidan, lipidperoksidasyon ve DNA hasarları karşılaştırıldı. Total oksidan durum (TOS) üremeöncesi gölden yakalanan balıkların karaciğer ve böbrek dokularında, totalantioksidan durum (TAS) ise akarsudan yakalanan balıklarda karaciğerde, göldenyakalanan balıkların ise beyin ve böbrek dokularında yüksek olduğu gözlendi(P<0.05). Malondialdehit (MDA) seviyelerinin akarsudan örneklenen balıklarınkaraciğerinde gölden örneklenen balıklarda ise böbreklerinde daha fazla olduğubelirlendi (P<0.05). DNA hasarınin ise sadece tatlı sudan örneklenenbalıkların karaciğerinde arttığı belirlendi. Sonuç olarak, Van Balığında üremegöçü sırasında karşılaşılan stres etkilerine karşı organların gösterdiğitepkiler belirlendi.
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UR  - https://doi.org/10.17798/bitlisfen.512275
L1  - https://dergipark.org.tr/en/download/article-file/668466
ER  -