TY - JOUR T1 - Evaluation of oxidative stress, antioxidant status and lipid profile in cattle with displacement of the abomasum TT - Abomazum deplasmanlı sığırlarda oxidatif stres, antioksidatif seviye ve lipit profilinindeğerlendirilmesi AU - Durgut, Ramazan AU - Sagkan Öztürk, Aliye AU - Ozturk, Oktay Hasan AU - Guzel, Murat PY - 2016 DA - June DO - 10.1501/Vetfak_0000002721 JF - Ankara Üniversitesi Veteriner Fakültesi Dergisi JO - Ankara Univ Vet Fak Derg PB - Ankara University WT - DergiPark SN - 1300-0861 SP - 137 EP - 141 VL - 63 IS - 2 LA - en AB - The aims of the present study were to evaluate serum oxidative and antioxidant status and oxidative stress index, and lipid metabolism profile in cattle with abomasal displacement. A total of thirty-two dairy cows with right- and left-sided abomasal displacement (LDA (n=11) and RDA without volvulus (n=11)) and 10 healthy controls were used in this study. Serum total oxidative status (TOS) and total antioxidant capacity (TAC) were measured by a colorimetric method. The TOS-to-TAC ratio was also calculated as oxidative stress index (OSI) value. Serum lipid profiles were determined by conventional measurement methods as well. Mean TOS and OSI values were significantly (p<0.001) higher in cows with RDA compared to LDA and healthy controls; however, there was no significant differences in serum TAC values among groups. Serum total cholesterol (TC), high density lipoproteins (HDL) and low density lipoproteins (LDL) levels were significantly (p=0.001) decreased, while serum triglyceride (TG) levels were significantly increased in dairy cows with right- and left-sided abomasal displacement compared to healthy controls. The results of current study showed that dairy cows with RDA forming free radicals than LDA and controls due to abomasal tension and increased intraluminal pressure KW - Dairy cow KW - displacement abomasum KW - oxidative stress N2 - Bu çalışmanın amacı abomazum deplasmanlı sığırlarda serum oksidan ve antioksidant seviyeleri ve okidatif stres indeksini (OSI) değerlendirmektir. Bu çalışmada toplam sağa ve sola abomasum deplasmanı olan 32 (11 sola deplasman, 11 volvulus olmayan sağa deplasman) ve 10 sağlıklı Holstein sığır kullanıldı. Serum toplam oksidan seviye (TOS) ve toplam antioksidan kapasite (TAC) kolarimetrik bir yöntemle belirlendi. OSI değeri, TAC-TOS oranı hesaplanarak belirlendi. Serum lipid profili ise geleneksel yöntemlerle belirlendi. TOS ve OSI değerleri, sola deplasmanlı sığırlar ve kontrol grubuyla karşılaştırıldığında sağa deplasmanlı sığırlarda önemli oranda (P<0.001) yüksek bulundu. Fakat serum TAC değerlerinde gruplar arasında önemli bir fark yoktu. Sağa ve sola deplasmanı olan sütçü sığırlar kontrolle karşılaştırıldığında serum trigliserit (TG) sevisinde önemli bir artış belirlenirken, serum total kolestrol (TC), yüksek dansiteli lipoproteinler (HDL) ve düşük dansiteli lipoprotein (LDL) seviyelerinde önemli bir azalma belirlendi. Bu çalışmanın sonuçlarında, RDA’lı sütçü sığırlar da intraluminal basınç artışı ve abomazumdaki gerginlikten dolayı LDA ve kontrollerden daha fazla serbest radikaller oluştuğu gösterildi CR - 1. Bernabucci U, Ronchi B, Lacetera N, et al. (2005): Influence of body condition score on relationships between metabolic status and oxidative stress in periparturient dairy cows. Journal of Dairy Science, 88, 2017-2026. CR - 2. Bobe G, Young JW, Beitz DC (2004): Invited Review: Pathology, etiology, prevention, and treatment of fatty liver in dairy cows. Journal of Dairy Science, 87, 3105- 3124. CR - 3. Cameron REB, Dyk PB, Herdt TH, et al. 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UR - https://doi.org/10.1501/Vetfak_0000002721 L1 - https://dergipark.org.tr/en/download/article-file/657068 ER -