TY - JOUR TT - Refractory Status Epilepticus After Ingestion of Amanita Virosa in an Epileptic Child AU - Konca, Çapan AU - Güneş, Ali AU - Kocamaz, Halil AU - Yel, Servet AU - Boşnak, Mehmet PY - 2014 DA - April JF - Journal of Emergency Medicine Case Reports PB - Acil Tıp Uzmanları Derneği WT - DergiPark SN - 2149-9934 SP - 110 EP - 112 VL - 5 IS - 4 KW - Amanita virosa KW - çocuk KW - mantar zehirlenmesi KW - refrakter KW - status epileptikus N2 - Introduction: Status epilepticus is considered refractory when seizure activity continues after receiving treatment with a benzodiazepine followed by infusion of traditional antiepileptic drugs. Mushroom poisoning may lead to variable clinical pictures. Although it is known that mushroom poisoning may develop epileptic seizures, there are no data about status epilepticus associated with amanita virosa mushroom poisoning in the literature. Case Report: A 6-year-old epileptic patient who regularly used antiepileptic drugs and had no seizures for 2 years was admitted to the emergency department due to refractory status epilepticus after ingestion of mushroom. Seizures that were refractory to antiepileptic therapy was controlled with intubation and mechanical ventilation after general anesthesia. Laboratory tests were normal, except elevated PTZ and aPTT. The patient, who had no additional problems and stabilized, was discharged on the fifth day of admission. Conclusion: We suggested that mushroom poisoning may reduce the threshold for seizures in our patient. In this study, it is emphasized that different clinical features may be found in a patient at the same time CR - Brophy GB, Bell R, Alldredge A, Bleck TP, Claassen J, LaRoche SM, et al. Neurocritical Care Society Status Epilepticus Guideline Neurocrit Care Writing Committee. Guidelines for the evaluation and management of status epilepticus. Neurocrit Care 2012; 17: 3-23. [CrossRef] CR - Mayer SA, Claassen J, Lokin J, Mendelsohn F, Dennis LJ, Fitzsimmons BF. Refractory status epilepticus: frequency, risk factors, and impact on outcome. Arch Neurol 2002; 59: 205-10. [CrossRef] CR - Kohn R, Mot’ovska Z. Mushroom poisoning: classification, symptoms and therapy. Vnitrni lekarstvi 1997; 43: 230-33. CR - Riviello JJ Jr, Claassen J, LaRoche SM, Sperling MR, Allredge B, Bleck TP et al. Treatment of status epilepticus: an international survey of experts. Neurocrit Care 2013; 18: 193-200. [CrossRef] CR - Piering WF, Bratanow N. Role of the clinical laboratory in guiding treatment of Amanita virosa mushroom poisoning: report of two cases. Clinical Chemistry 1990;36: 571-74. CR - Enjalbert F, Rapior S, Nouguier-Soulé J, Guillon S, Amouroux N, Cabot C. Treatment of amatoxin poisoning: 20-Year retrospective analysis. J Toxicol Clin Toxicol 2002; 40: 715-57. [CrossRef] CR - Leist M, Gantner F, Naumann H, Bluethmann H, Vogt K, Brigelius-Flohe R, et al. Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins. Gastroenterology 1997; 112: 923-34. [CrossRef] CR - Wittebole X, Hantson P. Use of the molecular adsorbent recirculating system (MARS) for the management of acute poisoning with or without liver failure. Clinical Toxicology 2011; 49: 782-93. [CrossRef] CR - Sorodoc L, Lionte C, Sorodoc V, Petris O, Jaba I. Is MARS system enough for A. phalloides-induced liver failure treatment? Human and Experimental Toxicology 2010; 29: 823-32. [CrossRef] CR - Schmidt LE, Dalhoff K. Risk factors in the development of adverse reactions to N-acetylcysteine in patients with paracetamol poisoning. British Journal of Clinical Pharmacology 2001; 51: 87-91. [CrossRef] UR - https://dergipark.org.tr/en/pub/jemcr/issue//535701 L1 - https://dergipark.org.tr/en/download/article-file/663526 ER -