TY - JOUR T1 - Comparison of fasting and postprandial levels of commonly used biochemical and hematological parameters TT - Sık kullanılan biyokimyasal ve hematolojik parametrelerin açlık ve postprandiyal düzeylerinin karşılaştırılması AU - Turan, Elif AU - Tunç, Recep AU - Turan, Yaşar PY - 2019 DA - August DO - 10.25000/acem.541810 JF - Archives of Clinical and Experimental Medicine JO - Arch Clin Exp Med PB - Mustafa HASBAHÇECİ WT - DergiPark SN - 2564-6567 SP - 66 EP - 71 VL - 4 IS - 2 LA - en AB - Aim: Physicians andpatients may have varying preferences for optimal blood analysis time. We aimedto determine the tendency for the optimal blood analysis time of the physiciansand patients and also to determine the difference in some commonly usedbiochemical and hematological parameters, between fasting and food intake. Methods: Questionnaireandcross-sectional designs were used. The doctors and patientswere conducted to a survey about the appropriate time for blood tests beforethe study. 112 patients were included in study. Blood samples were collectedafter 8-10 hours of fasting and 2 hours after 600-700 calories lunch. Bloodcreatinine, alanine aminotransferase, sodium, glucose, calcium, albumin, totalcholesterol, triglyceride, HDL, LDL, alkaline phosphatase, total bilirubin, lactatedehydrogenase, complete blood count, erythrocyte sedimentation rate, prothrombintime and TSH were studied and the values were compared.Results: In oursurvey, 75% of patients (54 patients in the outpatient clinic and 98 patientsin the blood collection unit, a total of 152) and 77% of doctors were thinkingthat fasting was the appropriate time for blood tests. There were significantincrease in glucose (p<0.01), triglyceride (p<0.01) and platelets (p=0.035)and significant decrease in sodium (p=0.01) after the food intake. There was nostatistically significant difference in the other parameters. Conclusion: Themajority of physicians and patients had the opinion that blood tests should begiven in fasting. Although there were significant differences in glucose, triglyceride, thrombocyte and sodium levels in our study, thrombocyte and sodium differencesmay not exhibit any clinical importance. Notwithstanding, high postprandiallevels of glucose and triglyceride are valuable indicators for cardiovasculardisease and diabetes risk. KW - Fasting KW - food intake KW - glucose KW - triglyceride N2 - Amaç: Hekimler vehastaların kan tahlili verme zamanı tercihleri değişiklik gösterebilmektedir. Çalışmamızdaanketler ile hekim ve hastaların eğilimlerini belirlemeyi ve günümüzde sıkkullanılan bazı biyokimyasal ve hematolojik tetkiklerde açlık ve toklukarasında farklılık olup olmadığını tespit etmeyi amaçladık.Materyal-metod:Anket ve kesitsel dizayn birlikte kullanıldı. Çalışmaya başlamadan öncedoktorlara ve hastalara kan tahlilleri için uygun kan verme zamanı konusundaanket yapıldı. Çalışmaya toplam 112 hasta alındı. Bu hastalarda 8-10 saatlikaçlık sonrası ve 600-700 kalorilik öğle yemeğinden 2 saat sonra kan alındı.Alınan kanlardan kreatinin, alanin aminotransferaz, sodyum, glukoz, kalsiyum,albumin, total kolesterol, trigliserid, HDL, LDL, alkalen fosfataz, totalbilirubin, laktat dehidrogenaz, hemogram, sedimentasyon, protrombiz zamanı veTSH çalışıldı ve değerleri karşılaştırıldı. Bulgular: Çalışmamızınanket evresinde; hastaların %75’i (54 poliklinik hastası ve 98 kan almabirimine gelen hasta olmak üzere toplam 152), doktorların % 77’si tetkiklerinaç karna yapılması gerektiğini düşünmekteydiler. Çalışılan kanların sonucundaglukoz (p<0.01), trigliserid (p<0.01) ve trombositlerde (p=0.035)toklukta istatistiksel olarak anlamlı artış, sodyumda (p=0.01) ise tokluktaanlamlı azalma tespit edildi. Diğer parametrelerde açlık ve tokluk arasındaistatistiksel olarak anlamlı farklılık bulunmadı. Sonuç: Doktor ve hastalarınbüyük çoğunluğu kan tetkiklerinin açlıkta verilmesi gerektiği görüşündedir.Çalışmamızda glukoz, trigliserid, trombosit ve sodyumda anlamlı farklılıktespit edilse de, trombosit ve sodyum düzeyindeki farklılık klinik önemarzetmeyecek seviyelerdeydi. Toklukta tespit edilen yüksek glukoz vetrigliserid düzeyleri kardiovasküler hastalık ve diyabet riski için kıymetligöstergelerdir. CR - 1. Kackov S, Simundic AM, Gatti-Drnic A. Are patients well informed about the fasting requirements for laboratory blood testing? Biochemia medica. 2013;23:326-31. 2. Adcock DM. Collection, transport, and processing of blood specimens for testing plasma-based coagulation assays and molecular hemostasis assays; approved guideline-fifth edition. January 2008. Available from: https://clsi.org/media/1399/h21a5_sample.pdf CR - 3. Complete blood count (CBC). 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