TY - JOUR T1 - Yenidoğan Yoğun Bakım Ünitesinde İdrar Yolu Enfeksiyonları: 4 Yıllık Deneyim TT - Urinary Tract Infections in Neonatal Intensive Care Unit: 4-Year Experience AU - Erol, Sara AU - Altuntaş, Nilgün PY - 2019 DA - March DO - 10.17098/amj.542422 JF - Ankara Medical Journal JO - Ankara Med J PB - Ankara Yildirim Beyazit University WT - DergiPark SN - 2148-4570 SP - 115 EP - 122 VL - 19 IS - 1 LA - tr AB - Amaç:Yenidoğan döneminde idrar yolu enfeksiyonu, term ve preterm bebekler içinönemli bir geç sepsis nedenidir. Bu çalışmanın amacı üçüncü düzey bir yenidoğanyoğun bakım ünitesine idrar yolu enfeksiyonu tanısıyla kabul edilen hastalarınklinik, laboratuvar ve radyolojik inceleme sonuçlarını değerlendirmektir. Materyalve Metot: Mesane kateterizasyonu ile alınan idrarkültürüne göre idrar yolu enfeksiyonu tanısı alan ve yenidoğan yoğun bakımünitesine kabul edilen term yenidoğanlara ait klinik, laboratuvar ve radyolojikgörüntüleme sonuçlarına geriye dönük olarak bilgisayar kayıtlarından ulaşıldı.Verilerin farklılıkları ve ilişkileri istatistiksel olarak değerlendirildi. Bulgular:2015-2018 yılları arasında idrar yolu enfeksiyonu tanısıyla yenidoğan yoğunbakımda izlenen 43 hastanın verileri değerlendirildi. Olguların %77 (n=30)’sierkekti ve ortalama tanı günü median 10 (7-28 gün) olarak bulundu. Olguların22(%51,16)’si sarılık, 6(%13,96)’sı kusma, 5(%11,62)’i ateş, 4(%9,30)’übeslenme güçlüğü yakınmaları ile başvururken %13,96’sının başvuru sırasında semptomuyoktu. En sık üreyen mikroorganizmalar %60,46 oranında Escherichia coli ve%20,93 oranında Klebsiella pneumonia idi. Amikasin direncinin Escherichia colive Klebsiella pneumonia üreyen hastalarda gentamisin direncine göre anlamlışekilde düşük olduğu görüldü (sırasıyla p<0,001 ve p=0,046). Sonuç:Neonatal idrar yolu enfeksiyonları klinik olarak asemptomatik olabileceklerigibi sepsis ve renal hasara yol açarak önemli morbidite ve mortalite nedeni deolabilirler. Erken ve etkin tedavi için klinik ve laboratuvar bulgularındeğerlendirilmesi kadar, değişken antibiyotik dirençlerinin dikkate alınarakampirik antibiyotik tedavisinin başlanması önemlidir.  KW - Yenidoğan KW - idrar yolu enfeksiyonu KW - antibiyotik direnci N2 - Objectives: Urinary tract infection in neonatal period is animportant cause of late sepsis for term and preterm infants. The aim of thisstudy was to evaluate the results of clinical, laboratory and radiologicalexaminations of patients admitted to the third-level neonatal intensive careunit with urinary tract infection.Materials and Methods: The results of clinical, laboratory and radiologicalimaging of term newborns who were diagnosed as urinary tract infectionaccording to urine culture obtained by bladder catheterization and acceptedinto neonatal intensive care unit were obtained from computer recordsretrospectively. Differences and relationships of the data were statisticallyevaluated.Results: The data of 43 patients who were followed up in the neonatal intensivecare unit with the diagnosis of urinary tract infection between 2015-2018 wereevaluated. 77 (n=30) % of the cases were male and the diagnosis day was median10 (7-28 days). 22 (51%) of the cases presented with jaundice, 6 (13.96%) withvomiting, 5 (11.62%) with fever and 4 (9.30%) with feeding difficulties and13.96% had no symptoms at admission. 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UR - https://doi.org/10.17098/amj.542422 L1 - https://dergipark.org.tr/en/download/article-file/675267 ER -