TY - JOUR TT - Evaluation of the Rate of Thrombocytosis in Lower Respiratory Tract and Upper Urinary System Infections AU - Güngör, Onur AU - Meral, Cihan AU - Karademir, Ferhan AU - Akcan, Abdullah Barış AU - Aydınöz, Seçil AU - Kul, Mustafa AU - Süleymanoğlu, Selami PY - 2011 DA - August JF - Meandros Medical And Dental Journal JO - Meandros Med. Den. j. PB - Aydin Adnan Menderes University WT - DergiPark SN - 2149-9063 SP - 1 EP - 3 VL - 12 IS - 2 KW - Reaktif trombositoz KW - üst üriner sistem enfeksiyonu KW - alt solunum yolu enfeksiyonu N2 - To evaluate the rates of thrombocytosis in lower respiratory tract (LRTI) and upper urinary system infections (UUSI). In this study, rates of thrombocytosis were evaluated in patients hospitalized and treated with the diagnosis of LRTI (n=20) or UUSI (n=22) in “GATA Haydarpasa Teaching Hospital, Department of Pediatrics” between 2006-2009, retrospectively. Reactive thrombocytosis is defined as the platelet count over 500.000/mm . Statistical analysis was performed by SPSS for Windows version 13.0. p≤0.05 was accepted as statistically significant. Thrombocytosis was found to be higher in the UUSI (%36) at the time of the diagnosis compared to the LRTI group (25%). The most common microorganism identified in the UUSI was Escherichia coli (n=12, 54%). There was no significant relationship between the reactive thrombocytosis observed at the time of the diagnosis and the severity of the disease in the LRTI and the UUSI CR - 1. Schafer AI. Thrombocytosis and thrombocytemia. Blood Rev 2001;15:159-66. CR - 2. Hollen CW, Henthorn J, Koziol JA, Burstein SA. Elevated serum interleukin-6 levels in patients with reactive thrombocytosis. Br J Haematol 1991;79:286- 90. CR - 3. Haznedaroğlu IC, Ertenli I, Ozcebe OI, et al. Megakaryocyte- related interleukins in reactive thrombocytosis versus autonomous thrombocthemia. Acta Haematol 1996;95:107-11. CR - 4. Dan K, Gomi S, Inokuchi K, et al. Effects of interleukin-1 and tumor necrosis factor on megakaryocytopoiesis: mechanism of reactive thrombocytosis.Acta Haematol 1995;93:67-72. CR - 5. Dame C, Sutor AH. Primary and secondary thrombocytosis in childhood. Br J Haematol 2005;129:165-77. CR - 6. Taksin AL, Couedic JP, Dusanter-Fourt I, et al. Autonomous megakaryocyte growth in essential thrombocythemia and idiopathic myelofibrosis is not related to a c-mpl mutation or to an autocrine stimulation by Mpl-L. Blood 1999;93:125-39. CR - 7. Schafer AI. Thrombocytosis. N Engl J Med 2004;350:1211-9. CR - 8. Eliot MA, Pardanani A, Lasho TL, Schwager SM, Tefferi A. Thrombosis in myelofibrosis: prior thrombosis is the only predictive factor and most venous events are provoked. Haematologica 2010;95:1788-91. CR - 9. Heits F, Stahl M, Ludwig D, Stange EF, Jelkmann W. Elevated serum thrombopoietin and interleukin-6 concentrations in thrombocytosis associated with inflammatory bowel disease. J Interferon Cytokine Res 1999;19:757-60. CR - 10. Vora AJ, Lilleyman JS. Secondary thrombocytosis. Arch Dis Child 1993;68:88-90. CR - 11. Chan KW, Kaikov Y, Wadsworth LD. Thrombocytosis in childhood: a survey of 94 patients. Pediatrics 1989;84:1064-7. CR - 12. Yohannan MD, Higgy KE, al-Mashhadani SA, Santhosh-Kumar CR. Thrombocytosis. Etiologic analysis of 663 patients. Clin Pediatr 1994;33:340-3. CR - 13. Catal F,Bavbek N, Bayrak O, et al. Platelet paramaters in children with upper urinary tract infection: Is there a specific response? Renal Failure 2008;30:377-81. CR - 14. Garoufi A, Voutsioti K, Tsapra H, Karpathios T, Zeis PM. Reactive thrombocytosis in children with upper urinary tract infections.Acta Peadiatr 2001;90:448-9. UR - https://dergipark.org.tr/en/pub/meandrosmdj/article/545397 L1 - https://dergipark.org.tr/en/download/article-file/681071 ER -