TY  - JOUR
TT  - Familial Testotoxicosis: A Case Report
AU  - Akyürek, Nesibe
AU  - Atabek, Mehmet Emre
AU  - Eklioğlu, Beray Selver
PY  - 2014
DA  - June
JF  - Türkiye Çocuk Hastalıkları Dergisi
JO  - Türkiye Çocuk Hast Derg
PB  - T.C. Sağlık Bakanlığı Ankara Şehir Hastanesi
WT  - DergiPark
SN  - 1307-4490
SP  - 0
EP  - 0
VL  - 8
IS  - 3
KW  - Ailevi testotoksikoz
KW  - Çocuk
KW  - Erken puberte
N2  - Testotoxicosis arises from testicular autoactivation due to LH receptor activating mutations and is a cause of false gonadotropin-independent precocious puberty. A male child aged 2 years and 3 months was admitted to our clinic with pubic hair in the genital area. He had a family history of precocious puberty in the father and the father’s male cousins. On physical examination skin and systemic fi ndings were normal, bilateral testis volume was 4 ml, stretched penile length was 4.5 cm, and pubic hair was Tanner stage 2. Although the testosterone levels were pubertal, baseline and stimulated LH levels were prepubertal.The patient was diagnosed with testotoxicosis with the family history, and clinical and biochemical evaluation.The case was presented because of its rarity
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UR  - https://dergipark.org.tr/en/pub/tchd/article/548978
L1  - https://dergipark.org.tr/en/download/article-file/687617
ER  -