@article{article_55538, title={Secondary Lymphoma in a Patient with a History of Unilateral Retinoblastoma}, journal={Cukurova Medical Journal}, volume={40}, pages={33–37}, year={2015}, DOI={10.17826/cutf.94994}, author={Kozanoğlu, Banu and Sezgin, Gülay and Bagır, Emine and Özkan, Ayse and Bayram, İbrahim and Tanyeli, Atila and Küpeli, Serhan}, keywords={lymphoma, retinoblastoma, second neoplasm, children}, abstract={Second malignancies develop with increased incidence in patients with herediter retinoblastoma. The most common second malignancies in retinoblastoma survivors are soft tissue sarcoma and osteosarcoma. Lymphoma developing as a second malignancy has rarely been reported. Here we report a case of lymphoma diagnosed in a 13 year-old-boy, 12 years after the diagnosis of unilateral retinoblastoma having heterozygous p.R552 (c.1654C> T) mutation, treated with enucleation and radiotherapy. The risk of second tumour is higher in the hereditary retinoblastoma, especially in cases undergoing external beam radiation therapy}, publisher={Cukurova University}