@article{article_566075, title={Plasma Nesfatin-1 Levels and its Relationship with Anxiety Levels in Obesity Diagnosed Population: A Controlled Study}, journal={Clinical and Experimental Health Sciences}, volume={9}, pages={107–111}, year={2019}, DOI={10.33808/clinexphealthsci.566075}, author={Baykan, Hayriye and Baykan, Ozgur and Durmaz, Onur and Gulsah, Oguz Elif and Kara, Hayrettin and Akdeniz Gorgulu, Serap and Yaman, Ali and Karlidere, Tunay}, keywords={Nesfatin-1,Obesity,Anxiety}, abstract={<p class="Metingdesi" style="text-align:justify;line-height:150%;">Objective: Nesfatin-1 is a satiety neuropeptide involved in the regulation of metabolic pathways and food intake. Some studies have shown nesfatin-1 to be also associated with stress responses and stress-related behaviors. In the present study, we evaluated nesfatin-1 levels in obese individuals and investigated whether nesfatin-1 levels could be associated with anxiety levels in obese populations. Methods: Fifty-eight obese (29 anxious and 29 non-anxious) patients and 25 healthy control subjects between 18 and 65 years old were enrolled in the study. Plasma nesfatin-1 levels were measured with a commercial enzyme-linked immunosorbent assay, and anxiety levels were measured using the Hospital Anxiety and Depression Scale. </p> <p class="Metingdesi" style="text-align:justify;line-height:150%;">Results: Plasma nesfatin-1 levels were significantly lower in both obese and anxious subjects and obese and non-anxious subjects than in the control group. No significant differences were found between the obese+anxious group and the obese+nonanxious group. </p> <p class="Metingdesi" style="text-align:justify;line-height:150%;">Conclusion: Our results suggest that plasma nesfatin-1 levels are decreased and not associated with anxiety levels in obese populations  </p>}, number={2}, publisher={Marmara University}