@article{article_570826, title={Antimicrobial Susceptibility Profiles and Prevalence of ESBLS among Escherichia coli Isolates Recovered from Clinical Specimens in Different Services}, journal={Middle Black Sea Journal of Health Science}, volume={5}, pages={186–191}, year={2019}, DOI={10.19127/mbsjohs.570826}, author={Cebeci, Tuğba and Keskin, Dilek and Gökal, Ahmet Ali}, keywords={E. coli,antibiotic sensitivity,clinical specimens}, abstract={<p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:normal;"> <b> <span style="font-family:’Times New Roman’, serif;">Objective: </span> </b> <span style="font-family:’Times New Roman’, serif;"> A
retrospective analysis of the widely used antibiotics all susceptibility
testing results from Escherichia coli cultured from clinical specimens private
hospital from (January 2016 to November 2018) was performed. </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:normal;"> <b> <span style="font-family:’Times New Roman’, serif;">Methods: </span> </b> <span style="font-family:’Times New Roman’, serif;"> The
VITEK 2 Compact automated microbiology system is designed for automated rapid
antimicrobial susceptibility testing and identification of clinically relevant
bacteria. Minimum inhibitory concentration (MIC) results previously obtained in
recent clinical isolates with well-defined in isolates with well-characterized
resistance mechanisms with the microdilution method were re-interpreted for the
susceptible, intermediate and resistant categories using the 2018 EUCAST
breakpoints. Clinical samples are most commonly isolated from blood, sputum and
urine samples. </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:normal;"> <b> <span style="font-family:’Times New Roman’, serif;">Results: </span> </b> <span style="font-family:’Times New Roman’, serif;">
Escherichia coli isolates were highly resistant to ampicillin, cefuroxime and
cefixime 79,16%, 60,41% and 58,33% respectively. Resistance rate of ceftriaxon
was showed in 52,08%. When we compared to resistance of
trimethoprim/sulfamethoxazole, Escherichia coli isolates showed 51,04%
resistance rate. When it comes to the most sensitive antibiotics, sensitivity
rate of fosfomycin, nitrofurantoin, ertapenem, imipenem, meropenem, gentamicin,
and amikacin were 89,58%; 91,66%; 93,75%; 93,75%; 94,79%; 83,33%; 84,37%
respectively. </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:normal;"> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:normal;"> <b> <span style="font-family:’Times New Roman’, serif;">Conclusion: </span> </b> <span style="font-family:’Times New Roman’, serif;">
Considering the antibiogram, fosfomycin, nitrofurantoin, ertapenem, imipenem,
meropenem, gentamicin and amikacin should be preferred drugs for E. coli
infection isolated from </span> <b> <span style="font-family:’Times New Roman’, serif;"> </span> </b> <span style="font-family:’Times New Roman’, serif;">clinical samples. </span> <b> <span style="font-family:’Times New Roman’, serif;"> </span> </b> <b> <span lang="en-us" style="font-size:9pt;font-family:’Times New Roman’, serif;" xml:lang="en-us"> </span> </b> </p> <p> <b> </b> </p> <b> </b> <p> <b> </b> </p> <b> </b>}, number={3}, publisher={Ordu University}