@article{article_581500, title={Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)}, journal={International Journal of Secondary Metabolite}, volume={6}, pages={317–322}, year={2020}, DOI={10.21448/ijsm.581500}, author={Mohammed, Falah Saleh and Pehlivan, Mustafa and Sevindik, Mustafa}, keywords={Antioxidant, Antibacterial, Antifungal, Medicinal Plants, Silybum marianum}, abstract={<div style="text-align:justify;"> <span style="font-family:’Times New Roman’, serif;font-size:11pt;">In this study, antioxidant, antibacterial and </span> <font color="#000000"> <a style="font-family:’Times New Roman’, serif;font-size:11pt;background-color:rgb(255,255,255);"> <font color="#000000">antifungal </font> </a> <span style="font-family:’Times New Roman’, serif;font-size:11pt;"> activities of </span> <i style="font-family:’Times New Roman’, serif;font-size:11pt;">Silybum marianum </i> <span style="font-family:’Times New Roman’, serif;font-size:11pt;"> (L.) Gaertn. collected from Duhok (Iraq) were determined. Ethanol, methanol and dichloromethane extracts of the fruit part of plant were obtained. Antioxidant potential was determined with TAS and TOS kits using ethanol extracts. Antibacterial and antifungal activity were determined using agar dilution method. Antibacterial activity was determined against 6 bacterial strains ( </span> <i style="font-family:’Times New Roman’, serif;font-size:11pt;">Staphylococcus aureus, S. aureus </i> <span style="font-family:’Times New Roman’, serif;font-size:11pt;"> MRSA, </span> <i style="font-family:’Times New Roman’, serif;font-size:11pt;">Enterococcus faecalis </i> <span style="font-family:’Times New Roman’, serif;font-size:11pt;">, </span> <i style="font-family:’Times New Roman’, serif;font-size:11pt;">Escherichia coli </i> <span style="font-family:’Times New Roman’, serif;font-size:11pt;">, </span> <i style="font-family:’Times New Roman’, serif;font-size:11pt;">Pseudomonas aeruginosa </i> <span style="font-family:’Times New Roman’, serif;font-size:11pt;"> and </span> <i style="font-family:’Times New Roman’, serif;font-size:11pt;">Acinetobacter baumannii </i> <span style="font-family:’Times New Roman’, serif;font-size:11pt;">). Antifungal activity was determined against </span> <i style="font-family:’Times New Roman’, serif;font-size:11pt;">Candida albicans, C. krusei </i> <span style="font-family:’Times New Roman’, serif;font-size:11pt;"> and </span> <i style="font-family:’Times New Roman’, serif;font-size:11pt;">C. glabrata </i> <span style="font-family:’Times New Roman’, serif;font-size:11pt;">. As a result of the studies, it was determined that plant extracts have high antioxidant activity. It was also found to be effective against bacteria at 25-400 µg/mL concentrations. </span> <span style="font-family:’Times New Roman’, serif;font-size:11pt;">  </span> <span style="font-family:’Times New Roman’, serif;font-size:11pt;">Plant extracts were found to be more effective against gram negative bacteria. It was found to be effective against </span> <i style="font-family:’Times New Roman’, serif;font-size:11pt;">Candida </i> <span style="font-family:’Times New Roman’, serif;font-size:11pt;"> species at 400-800 µg/mL concentrations. As a result, it was determined that the fruit parts of plant could be a natural antioxidant and antibacterial source. </span> </font> </div>}, number={4}, publisher={İzzet KARA}