TY  - JOUR
T1  - Retinal Ven Tıkanıklığına Bağlı Oluşan Maküler Ödem Tedavisinde İntravitreal Deksametazon İmplantın Erken Dönem Sonuçları
TT  - Early Results of the Intravitreal Dexamethasone Implant in the Treatment of Macular Edema Due to Retinal Vein Occlusion
AU  - Konuk, Şerife Gülhan
AU  - Ekşi Yücel, Özlem
AU  - Can, Ertuğrul
PY  - 2019
DA  - June
Y2  - 2019
DO  - 10.16899/gopctd.534198
JF  - Journal of Contemporary Medicine
JO  - J Contemp Med
PB  - Rabia YILMAZ
WT  - DergiPark
SN  - 2667-7180
SP  - 163
EP  - 166
VL  - 9
IS  - 2
LA  - tr
AB  - Amaç:Santral retinal ven tıkanıklığı (SRVT) ve retinal ven dal tıkanıklığına (RVDT)bağlı oluşan maküler ödem (MÖ) tedavisinde deksametazon implantın altı aylıketkisini ve yan etkilerini değerlendirmek. Gereç: Göz Hastalıkları KliniğindeSRVT (n=19) ve RVDT(n=18) sonucu oluşan MÖ nedeniyle tek doz intravitrealdexametazon implant ile tedavi edilen 37 hasta (37 göz) çalışmaya dahil edildi.Hastaların kayıtları retrospektif olarak incelendi. En az 6 ay boyunca, aylıkolarak takip edilen hastalar çalışmaya dahil edildi. Başlangıç ve tedavisonrası her kontrolde yapılmış olan; biyomikroskopik muayene bulguları, en iyidüzeltilmiş görme keskinliği (EDGK) düzeyi ve spektral domain optik koherenstomografi (OKT) ile santral maküler kalınlık (SMK) ölçümleri ve yan etkilerkaydedilerek değerlendirildi. Bulgular:RVDT olguları grup 1 (n=18), SRVT olguları grup 2 (n=19) olmak üzere hastalar 2gruba ayrıldı. Tüm hastalarda tedavi sonrası EDGK 4. aya kadar anlamlıolarak artarken SMK değerleri anlamlı olarak azaldı (p<0.05). Tedavinin 4.ayından sonra ise EDGK değeri tedavi öncesine göre istatistiksel olarak farklıdeğildi. Maximum görme keskinliğindeki artış grup 2’ye kıyasla grup 1’deanlamlı olarak fazla idi. İki grup arasında ortalama SMK azalması açısındanistatistiksel olarak anlamlı bir fark bulunmadı (p>0.05). Tedavi edilen 8hastada (%21,6) göz içi basınç artışı görüldü. Sonuç:SRVT ve RVDT’na ikincil maküler ödem olgularında intravitreal dexametazon implant,ilk 6 ayda anatomik ve fonksiyonel düzelme sağlamıştır. Göz içi basıncı artışıdışında yan etki görülmemiştir.
KW  - Deksametazon implant
KW  - maküler ödem
KW  - retinal ven tıkanıklığı
N2  - Introduction: Toevaluate the six-month effect and side effects of dexamethasone implant in thetreatment of central retinal vein occlusion (SRVT) and retinal vein branchocclusion (RVDT) induced macular edema (MO).Material and Method:Thirtyseven patients (37 eyes) who were treated with intravitreal dexamethasoneimplant due to SRVT (n = 19) and RVDT(n = 18) in the Ophthalmology Departmentwere included in the study. Records of patients were reviewed retrospectively.Patients who were followed up monthly for at least 6 months were included inthe study. It was performed at the beginning and after each treatment;slit-lamp biomicroscopic examination findings, best corrected visual acuity(EDGK), spectral domain optical coherence tomography (OKT) and central macularthickness (SMK) measurements were done and side effects were recorded.Results: Thepatients were divided into two groups: RVDT group 1 (n = 18), SRVT group 2 (n =19). In all patients, after the treatment, EDGK increased significantly up tothe 4th month, whereas the values ​​of SMK decreased significantly (p<0.05).There was no significant difference between EDGK after the 4th month. Theincrease in maximum visual acuity was significantly higher in group 1 than 2.There was no statistically significant difference between the two groups interms of mean SMK reduction (p>0.05). In 8 (21.6%) patients treated withintravitreal dexamethasone implant, intraocular pressure increased.Discussion:Intravitreal dexamethasone implant provides anatomic and functional improvementin the first 6 months in patients with macular edema secondary to SRVT andRVDT. No side effects were seen except intraocular pressure.
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UR  - https://doi.org/10.16899/gopctd.534198
L1  - https://dergipark.org.tr/en/download/article-file/747307
ER  -