TY - JOUR T1 - Endoscopic Surgery of Urethral Strictures: Laser Versus Knife TT - Üretra Darlığında Endoskopik Cerrahi: Bıçağa Karşı Lazer AU - Solakhan, Mehmet AU - Bayrak, Ömer PY - 2020 DA - February DO - 10.33719/yud.590392 JF - Yeni Üroloji Dergisi JO - New J Urol. PB - Ali İhsan TAŞÇI WT - DergiPark SN - 1305-2489 SP - 39 EP - 44 VL - 15 IS - 1 LA - en AB - Aims:We aimed to compare the efficiency of cold knife urethrotomy andlaser urethrotomy in endoscopic surgery of urethral strictures. Material-Methods:A total of 171 patients were evaluated retrospectively. A 118patients with complete data were divided into two groups (group 1; n= 53 cold knife urethrotomy, group 2; n = 65 laser urethrotomy) inthe study. Length of the stricture, operation time, preoperative andpostoperative 3rd,6thand 12th-monthQmax values, recurrence and the presence of complications (such asbleeding, extravasation, fever etc.) were compared in terms of thetwo groups. Results:The operation time was found to be shorter in patients who underwentcold knife urethrotomy (14.01 ± 3.86 min vs 25.03 ± 4.43 min,p=0.001). The Q max values at the postoperative 3rd,6thand 12thmonths were observed to be higher in patients who underwent laserurethrotomy (p=0.03, p=0.001, p=0.001). At the end of a one-yearfollow-up, recurrence was determined in 28 (52.83%) patients in group1 and 12 (18.46%) patients had a recurrencein group 2 (p=0.01). Nostatistically significant difference was observed between the twogroups in terms of postoperative complications. (p=0.209).Conclusions:In this study, it was determined that laser urethrotomy technique wasa more successful surgical method than cold knife urethrotomy in theendoscopic surgery of urethral strictures as it has higher Qmaxvalues and lower recurrence rate. The results should be supported byprospective, randomized studies. KW - urethral stricture KW - laser urethrotomy KW - cold knife KW - nux N2 - Amaç:Üretra darlığının endoskopik cerrahisinde cold knife üretrotomiile laser üretrotominin etkinliğini karşılaştırmayı amaçladık.Materyal-metod:Toplam171 hasta retrospektif olarak değerlerlendirildi. Çalışmakapsamında verileri tam olan 118 hasta 2 gruba ayrıldı (grup 1;n=53 cold knife üretrotomi, grup 2; n= 65 lazer üretrotomi).Darlığın uzunluğu, operasyon süresi, preoperatif vepostoperatif 3., 6. ve12. aylardaki Qmax değerleri, nüks olupolmadığı ve komplikasyon varlığı (kanama, extravazasyon, ateşgb) açısından iki grup karşılaştırıldı. Bulgular:Operasyon zamanının cold knife üretrotomi yapılan hastalarda dahakısa olduğu görüldü (14.01 ± 3.86 dk vs 25.03 ± 4.43 dk,p=0.001). Postoperatif 3., 6., ve 12. aylardaki Q max değerlerinin lazer üretrotomi yapılan hastalarda daha yüksek olduğu görüldü(p=0.03, p=0.001, p=0.001). Bir yıllık takip sonucunda grup-1' de28 (52.83%) hastada nüks saptanırken, grup-2' de 12 (18.46%)hastada nüks geliştiği gözlendi (p=0.01). Postoperatifkomplikasyonlar açısından her iki grup arasında istatiksel olarakanlamlı fark izlenmedi. (p=0.209).Sonuç:Yaptığımızbu çalışmada üretra darlığını endoskopik cerrahisinde, lazerüretrotomi tekniğinin, coldknife üretrotomiye göre yüksek Qmax değerlerine ve daha düşüknüks oranına sahip olması nedeniyle daha başarılı bir cerrahiyöntem olduğu saptanmıştır. Sonuçların prospektif, randomizeçalışmalarla desteklenmesi gerekmektedir. CR - 1. Sachse H. Treatment of urethral stricture: transurethral slit in view using sharp section. Fortschr Page Med. 1974; 92: 12-15. CR - 2. Jin T, Li H, Jiang LH, Wang L, Wang KJ. Safety and efficacy of laser and cold knife urethrotomy for urethral stricture. Chin Med J. 2010;123(12):1589–95. CR - 3. Waseem Aboulela, Mohammed S, El Sheemy Mahmoud Shoukry, Ahmed M Shouman, Ahmed I.Shoukry, Waleed Ghoneima1 Mohamed El Ghoneimy, et all. Visual internal urethrotomy for management of urethral strictures in boys: a comparison of short-term outcome of holmium laser versus cold knife. Int Urol Nephrol. 2018 Apr;50(4):605-609. doi: 10.1007/s11255-018-1809-x. CR - 4. Torres Castellanos L, Moreno Bencardino MC, Bravo-Balado A, García Mayorga CA, Vargas Manrique I, Fernández N. Evaluation of the Efficacy and Safety of Laser versus Cold Knife Urethrotomy in the Management of Patients with Urethral Strictures: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Urol Int. 2017;99(4):453-459. doi: 10.1159/000478026. Epub 2017 Jul 12. CR - 5. Hussain M, Lal M, Askari SH, et al. Holmium laser urethrotomy for treatment of traumatic stricture urethra: A review of 78 patients. J Pak Med Assoc 2010;60:829-32. CR - 6. Herrmann TR, Liatsikos EN, Nagele U, et al. EAU guidelines on laser technologies. Eur Urol 2012;61:783-95. http://dx.doi.org/10.1016/j.eururo.2012.01.010. CR - 7. Farrell MR, Sherer BA, Levine LA. Visual internal urethrotomy with intralesional mitomycin c and short-term clean intermittent catheterization for the management of recurrent urethral strictures and bladder neck contractures. Urology. 2015;85(6):1494–9. CR - 8. Hampson LA, Mcaninch JW, Breyer BN. Male urethral strictures and their management. Nat Rev Urol. 2014;11(1):43–50. CR - 9. Dubey D. The current role of direct vision internal urethrotomy and self-catheterization for anterior urethral strictures. Indian J Urol (Internet). 2011;27(3):392. CR - 10. Santucci R, Eisenberg L. Urethrotomy has a much lower success rate than previously reported. J Urol. 2010;183(5):1859–62. CR - 11. Al Taweel W., Seyam R. Visual internal urethrotomy for adult male urethral stricture has poor long-term results. Adv Urol. 2015;2015: 1–4. CR - 12. Pal D, Kumar S, Ghosh B. Direct visual internal urethrotomy: is it a durable treatment option? Urol Ann (Internet). 2017;9(1):18. CR - 13. Yıldırım ME, Kaynar M, Ozyuvali E, et al. The effectiveness of local steroid injection after internal urethrotomy to avoid recurrence. Arch Ital Urol Androl. 2015;87(4):295–8. CR - 14. Kumar S, Kishore L, Sharma AP, Garg N, Singh SK. Efficacy of holmium laser urethrotomy and intralesional injection of Santosh PGI tetra-inject (triamcinolone, mitomycin c, hyaluronidase and nacetyl cysteine) on the outcome of urethral strictures. Cent Eur J Urol. 2015;68(4):462–5. CR - 15. Tamsin J. Greenwell, Carissa Castle & David L. Nicol (2016) Clean intermittent self-catheterization does not appear to be effective in the prevention of urethral stricture recurrence, Scandinavian Journal of Urology, 50:1, 71-73. DOI: 10.3109/21681805.2015.1086888. CR - 16. Atak M, Tokgöz H, Akduman B, Erol B, Dönmez I, Hancı V, Türksoy O, Mungan NA. Low-power holmium:YAG laser urethrotomy for urethral stricture disease: comparison of outcomes with the cold-knife technique. Kaohsiung J Med Sci. 2011 Nov;27(11):503-7. doi: 10.1016/j.kjms.2011.06.013. CR - 17. Ankur Jhanwar, Manoj Kumar, Satya Narayan Sankhwar, Gaurav Prakash. Holmium laser vs. conventional (cold knife) direct visual internal urethrotomy for short-segment bulbar urethral stricture: Outcome analysis. Can Urol Assoc J 2016;10(5-6):E161-4. http://dx.doi.org/10.5489/cuaj.3382. CR - 18. Albers P, Fichtner J, Bruhl P, et al. Long-term results of internal urethrotomy. J Urol 1996;156:1611-4. http://dx.doi.org/10.1016/S0022-5347(01)65461-2. CR - 19. Dutkiewicz SA, Wroblewski M. Comparison of treatment results between holmium laser endourethrotomy and optical internal urethrotomy for urethral stricture. Int Urol Nephrol 2012;44:717-24. http://dx.doi. org/10.1007/s11255-011-0094-8. UR - https://doi.org/10.33719/yud.590392 L1 - https://dergipark.org.tr/en/download/article-file/966353 ER -