@article{article_594637, title={The Hemoglobin-Red Cell Distribution Width and Neutrophil -Lymphocyte Ratio in Predicting Lamina Propria Invasion in Bladder Tumors?}, journal={Yeni Üroloji Dergisi}, volume={15}, pages={11–18}, year={2020}, DOI={10.33719/yud.594637}, author={Türkoğlu, Ali Rıza and Üstündağ, Yasemin and Çoban, Soner and Güzelsoy, Muhammet and Öztürk, Murat and Satır, Atilla and Demirci, Hakan and Huysal, Kağan}, keywords={Non-muscular invasive bladder cancer,Hemoglobin-red cell distribution width ratio,Neutrophil-lymphocyte ratio,Lamina propria invasion.}, abstract={<p class="MsoNormal" style="line-height:200%;"> <span style="line-height:200%;font-size:14px;">Purpose: </span> <span style="line-height:200%;font-size:14px;">
To investigate the importance of the Hemoglobin/Red cell distribution width
ratio (Hb/RDW) and Neutrophil/Lymphocyte ratio (NLR) in predicting bladder
lamina propria invasion before transurethral resection in non-muscular invasive
bladder cancer (NMIBC) patients </span> </p> <p> </p> <p class="MsoNormal" style="line-height:200%;"> <span style="line-height:200%;font-size:14px;">Methods: </span> <span style="line-height:200%;font-size:14px;">
The data of the patients whose pathology after transurethral resection of the
bladder was NMIBC between January 2010 and June 2016 were evaluated
retrospectively. Group 1 had Ta (mucosa involvement) and Group 2 had T1
(submucosa involvement) lesions. The age, gender, tumor size and number of
tumors of the patients were identified. The preoperative blood leucocyte (WBC),
hemoglobin (Hb), neutrophil (N), lymphocyte (L), monocyte (M), platelet (PLT),
mean platelet volume (MPV), and red cell distribution width (RDW) values were
identified and the NLR, PLR, LMR values calculated. The Hb/RDW ratio was
determined. </span> </p> <p> </p> <p class="MsoNormal" style="line-height:200%;"> <span style="line-height:200%;font-size:14px;">Results: </span> <span style="line-height:200%;font-size:14px;"> A
total of 369 patients were evaluated. The mean age was similar between groups.
Group 1 (Ta) consisted of 219 patients (66.3±10.7 years) and Group 2 (T1) 150
patients (66.9±10.4 years) (p=0.638). NLR was higher in Group 2 than Group 1
(2.4 (1.5) and 2.2 (1.5), respectively, p=0.042) and this difference was
statistically significant. The Hb/RDW ratio in Group 2 was lower than in Group
1 (0.89±21 and 0.94±19, respectively, p=0.019) and this difference was
statistically significant. </span> </p> <p> </p> <p class="MsoNormal" style="line-height:200%;"> <span style="line-height:200%;font-size:14px;">Conclusion: </span> <span style="line-height:200%;font-size:14px;">
We believe that a decrease in the Hb/RDW ratio and increase in NLR, which can
be easily determined from the peripheral blood in the preoperative period, can
be associated with lamina propria invasion (T1). These studies should be
supported with prospective large series. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <span style="line-height:200%;"> </span> </p> <p> <span style="font-size:14px;">  </span> </p> <p> <span style="font-size:14px;"> </span> </p> <p class="MsoNormal" style="line-height:200%;"> <br /> </p> <p> </p>}, number={1}, publisher={Ali İhsan TAŞÇI}