@article{article_594839, title={Characterization of Secondary Metabolites in Two Cousinia species}, journal={International Journal of Secondary Metabolite}, volume={6}, pages={333–341}, year={2020}, DOI={10.21448/ijsm.594839}, author={Paşayeva, Leyla and Fatullayev, Hanifa and Karakuş, İrem Nur and Soylu, Serap and Tugay, Osman}, keywords={Cousinia, Asteraceae, LC-MS/MS, Rutin, Flavonoid}, abstract={<div style="text-align:justify;"> <i> <span lang="en-gb" style="font-size:11pt;line-height:107%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">Cousinia </span> </i> <span lang="en-gb" style="font-size:11pt;line-height:107%;font-family:’Times New Roman’, serif;" xml:lang="en-gb"> is one of the widespread genera of Asteraceae family.
According to previous studies on some <i>Cousinia </i>species it was found that these species are rich of triterpenes,
sesquiterpenes, flavonoids, acetylenes and steroids. According to our
knowledge, there are no published reports on the chemical composition of <i>C. iconica </i> Hub. - Mor. and <i>C. aintabensis </i> Boiss. & Hausskn.,
thus we aimed to investigate secondary metabolites of these species. In this
study, the phytochemical <a> <font color="#000000">constituents </font> </a> of these
species were evaluated. Seven of identified compounds were quantified. The
quantitative and qualitative determination of compounds within the extracts was
carried out by LC-MS/MS.  Phytochemical
analyses revealed the presence of flavonoids, saponins, terpenes and steroids.
Preliminary examination of the mass spectrums revealed the presence of phenolic
acids and derivatives and flavonoid compounds in extracts. According to
quantitative analyses the main compound of <i>C.
iconica </i> (CI) <i> </i>and <i> C. aintabensis </i> (CA) extracts was rutin
with the highest contents (169.779 µg/mg <sub>extract </sub>and 161.638 µg/mg <sub>extract </sub>). </span> <span style="font-size:11pt;line-height:107%;font-family:’Times New Roman’, serif;">Moreover, qualitative and quantitative study combined
with different biological activities will shed new lights to the advanced
studies. </span> <br /> </div>}, number={4}, publisher={İzzet KARA}, organization={Erciyes University Scientific Research Projects Coordinating Unit (BAP)}