@article{article_595147, title={In vitro Antiradical, Antimicrobial and Antiproliferative Activities and Phytochemical Compositions of Endemic Alcea calvertii (Boiss) Boiss. Flowers}, journal={Duzce University Journal of Science and Technology}, volume={8}, pages={693–701}, year={2020}, DOI={10.29130/dubited.595147}, author={Keser, Serhat and Keser, Fatma and Tekın, Suat and Kaygılı, Ömer and Turkoglu, İsmail and Demır, Ersin and Karatepe, Mustafa and Kırbag, Sevda and Yılmaz, Ökkes and Sandal, Suleyman and et al.}, keywords={Alcea calvertii,antiradical,antimicrobial,antiproliferative,phytosterol}, abstract={<p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;"> <i> <span style="font-size:10pt;line-height:115%;font-family:’Times New Roman’, serif;" lang="en-us" xml:lang="en-us">Alcea calvertii </span> </i> <span style="font-size:10pt;line-height:115%;font-family:’Times New Roman’, serif;" lang="en-us" xml:lang="en-us"> (Boiss) Boiss.
is belonged to Malvaceae family, and it is a perennial herbaceous endemic
plant. <i>Alcea </i> genus plants are grown
as ornamental plants in the gardens. In the present study, the antiproliferative,
antimicrobial, antiradical activities and phytochemical compositions of
ethanol, water, methanol and acetone extracts of <i>A. calvertii </i> flowers were examined. <i>A. calvertii </i> flowers water, ethanol, methanol and acetone extracts
are lower scavenged DPPH, ABTS and OH radicals than standard antioxidant
trolox. <i>A. calvertii </i> flowers contain
vitamins, sterols, flavonoids and phenolic acids, dominated by vanillic acid,
gallic acid, catechin, δ-tocopherol, ergosterol and vitamin D. A. calvertii
flowers water extract showed better antiproliferative activities than other
extracts against to MCF-7 and HCT-116 cell lines. <i>A. calvertii </i> flowers methanol extract showed higher
antiproliferative effect against to LNCaP cell lines. </span> </p>}, number={1}, publisher={Duzce University}, organization={TÜBİTAK}