TY - JOUR T1 - OPTIMIZATION OF ULTRASOUND-ASSISTED EXTRACTION OF OLIVE LEAF (var. HALHALI) EXTRACTS AU - Ünver, Naciye AU - Çelik, Şerafettin PY - 2022 DA - February Y2 - 2022 DO - 10.15671/hjbc.595565 JF - Hacettepe Journal of Biology and Chemistry JO - HJBC PB - Hacettepe University WT - DergiPark SN - 2687-475X SP - 173 EP - 184 VL - 50 IS - 2 LA - en AB - In this study, the effects ofthree different independent variables (extraction temperature, extraction time,ultrasonic power) on the total phenolic content, extraction yield andantioxidant capacity (IC50) value of olive leaf extracts of Halhalıvariety which is originated from South-eastern Anatolia Region wereinvestigated. As a result of the evaluation made with Box-Behnken Design Model,the optimum conditions were determined as 62.94°C, 50.67 min, and 64.65%ultrasonic power for the optimization of ultrasonic-assisted extraction. In order to visualize the effect ofextraction method on TPC, extraction yield and IC50 value of oliveleaf extracts, results of three extraction methods were compared. Thedifferences among the mean values of the investigated parameters in terms ofextraction method were found significantly different (P<0.05). In addition, it can be inferenced thatultrasound assisted extraction accelerated the transition of phenolicsubstances to solvent in terms of SEM images and investigated other parameters. KW - Olive leaf extract KW - Halhalı variety KW - ultrasound assisted extraction KW - optimization CR - 1. Á. Guinda, Use of solid residue from the olive industry, Grasas y Aceites, 57 (2006) 107–115. CR - 2. N. Bahloul, N. Boudhrioua, M. Kouhila, N. Kechaou, Effect of convective solar drying on colour, total phenols and radical scavenging activity of olive leaves (Olea europaea L.), Int. J. Food Sci. Technol,44(2009) 2561–2567. CR - 3. A. Moure., J.M. Cruz., D. France., J.M. Dominguez., J. 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Ekateriniadou, Optimization of ultrasound-assisted extraction of phenolic compounds: Oleuropein, phenolic acids, phenolic alcohols and flavonoids from olive leaves and evaluation of its antioxidant activities. Industrial Crops and Products, 124(2018) 382-388. UR - https://doi.org/10.15671/hjbc.595565 L1 - https://dergipark.org.tr/en/download/article-file/768127 ER -