TY  - JOUR
T1  - The evaluation of the oxidative stress index of reproductive tissues and serum thiol/disulphide homeostasis during estrous cycle in bitches
AU  - Baki Acar, Duygu
AU  - Demirel, Mürşide Ayşe
AU  - Dizakar Akarca, Saadet Özen
AU  - Birdane, Muhammed Kürşad
PY  - 2019
DA  - December
DO  - 10.33988/auvfd.604496
JF  - Ankara Üniversitesi Veteriner Fakültesi Dergisi
JO  - Ankara Univ Vet Fak Derg
PB  - Ankara University
WT  - DergiPark
SN  - 1300-0861
SP  - 87
EP  - 94
VL  - 67
IS  - 1
LA  - en
AB  - The aim of this study was firstly to determinethe relationship between estrous cycle and oxidative stress in reproductivetissues in bitches. This research was performed in twenty-nine healthy bitchesfrom different breeds and of varied ages (the range was 2-5 years) that werebrought to the clinic for routine ovariohysterectomy. The stages of estrouscycle were detected using by vaginal cytology, blood progesterone level andhistological findings. Ovarian, oviduct and uterine tissues were taken into Eppendorftubes for oxidative stress index and stored at -80°C until analyses. Also, anotherpart of these tissues were fixed in 10% formalin solution. There were nosignificant differences (P > 0.05) among total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) values in the reproductive tissues inconcerning estrous cycle stages. However, there were remarkable correlationsbetween oxidative stress parameters and reproductive tissues in differentestrus stages in bitches. Inconclusion, the physiological values of TAS and TOS concentration, and OSI inthe ovarian, oviduct and uterine tissues during estrous cycle were firstlydefined in this article. The serum thiol/disulphide homeostasis was alsodetermined in the estrous cycle of bitches. We have found that there areremarkable variations of oxidative stress balance in the ovary, oviduct anduterus concurrently, during estrous cycle in the bitches. Besides, significantcorrelations between oxidative stress parameters and estrous cycle stages inthe reproductive tissues were observed in the present study.
KW  - Bitch
KW  - estrous
KW  - oxidative stress index
KW  - progesterone
KW  - thiol/disulphide
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UR  - https://doi.org/10.33988/auvfd.604496
L1  - https://dergipark.org.tr/en/download/article-file/901754
ER  -