TY - JOUR T1 - Taşınabilir Lipid Analizörü Cardıocheck (Tm) Performansı TT - Performance of Cardiocheck (Tm) Portable Lipid Analyser AU - Buğdaycı, Güler AU - Sezer, Sevilay AU - Koca, Yüksel AU - Turhan, Turan PY - 2005 DA - December JF - Duzce Medical Journal JO - Duzce Med J PB - Duzce University WT - DergiPark SN - 1307-671X SP - 5 EP - 9 VL - 7 IS - 3 LA - tr AB - Yeni kullanılmaya başlayan CardioCheck(TM) taşınabilir lipid analizörünün, NCEP’e (National Cholesterol Education Program) göre değerlendirilmesi amaçlanmıştır. Total Kolesterol (TK), HDL Kolesterol (HDL-K) ve Trigliserid (TG) düzeyleri saptamak için, polikliniğe gelen yüz hasta çalışmaya dahil edilmiştir. Örnekler eş zamanlı olarak CardioCheck(TM) lipid analizöründe ve Biyokimya Laboratuvarında otomatik enzimatik metod ile çalışıldı. Tekrarlanabilirlik çalışması, normal ve yüksek kontrol serumunda yirmişer kez saptandı. Tekrarlanabilirlik çalışmasının varyasyon katsayısı (% CV) sonuçları; panel TK % 3.29 ( NCEP % ≤ 3) , panel HDL-K % 6.1 ( NCEP ≤ %6), panel TG % 18.9 ( NCEP ≤ % 5), TK % 5.3, HDL-K % 14.5, TG % 15.7 idi. CardioCheck(TM) tekrarlanabilirlik sonuçları NCEP’e göre değerlendirildi. CardioCheck(TM) lipid analizörünün geleneksel rutin ölçüme bir seçenek olacak kadar güvenilir olmadığı ortaya kondu KW - Serum Lipidleri KW - Hasta Başı Testler KW - Lipid Analizörü N2 - To verify whether precision of lipids analyses by a new portable device, CardioCheck(TM), were in agreement with the guidelines of the National Cholesterol Education Program (NCEP). Serum samples from hundred outpatients were collected for the determination of total Cholesterol (TC), HDL-cholesterol (HDL-C) and triglycerides (TG). These samples were analysed simultaneously by the CardioCheck(TM), and by the automatic enzymatic methods routinely used at the biochemistry laboratory. Precision was determined by repeating 20 times the evaluation of normal and high control sera. Precision for panel TC was 3.29 % (NCEP ≤ 3 %), for panel HDL-C was 6.1 % (NCEP ≤ 6%) and for panel TG was 18.9 % (NCEP ≤ 5 %), TC was 5.3 % , HDL-C 14.5 % , TG was 15.7 %. Precision lipids evaluation by the CardioCheck(TM) are within the guidelines of the NCEP. Therefore the CardioCheck(TM) seems to be a nonreliable alternative to the conventional biochemical routine CR - National Cholesterol Education Program. Report of the expert panel on detection, evaluation, and treatment of high cholesterol in adults. Arch Intern Med. 148: 36-9, 1998. CR - National Cholesterol Education Program. Third report of the National Cholesterol Education Program on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) executive summary. NIH Publication Number 01-3670, 2001. CR - Caudill SP, Cooper GR, Smith SJ, Myers GL: Assessment of current National Cholesterol Education Program guidelines for total cholesterol, triglyceride, HDL-cholesterol, and LDL-cholesterol measurements. Clin Chem. 44:1650-8, 1998. CR - Issa JS, Strunz C, Giannini SD, Forti N, Diament J: Precision and accuracy of blood lipid analyses by a portable device (Cholestech-LDX) Arq Bras Cardiol.66:339-42, 1996. CR - Volles DF, Mc Kenney JM, Miller WG, Ruffen D, Zhang D: Analytic and clinical performance of two compact cholesterol-testing devices. Pharmacotherapy.18:184-92, 1998. CR - Warnick GR: Measurement of cholesterol and other lipoprotein constituents in the clinical laboratory. Clin Chem Lab Med.38:287-300, 2000. CR - Kafonek SD, Donovan L, Lovejoy KL, Bachorik PS: Biological variation of lipids and lipoproteins in fingerstick blood. Clin Chem. 42:2002-7, 1996. CR - Rubin DA, McMurray RG, Harrell JS, Carlson BW, Bangdiwala S: Accuracy of three dry- chemistry methods for lipid profiling and risk factor classification. Int J Sport Nutr Exerc Metab.13:358-68, 2003. CR - Rogers EJ, Misner L, Ockene IS, Nicolasi RJ: Evaluation of Seven Cholestech LDX Analyzers for total cholesterol determinations. Clin Chem.39: 860-4,1993. CR - Bard RL, Kaminsky LA, Whaley MH, Zajakowski S: Evaluation of lipid profile measurements obtained from the Cholestech LDX analyzer. J Cardiopulm Rehabil. 17:413-8, 1997. CR - McKenney JM, Fary DF, Miller G, Proctor JD, Chinchili VM: An evaluation of two compact analyzers used for lipid analysis. J Fam Pract.36:526-33, 1993. CR - Volles DF, McKenney JM, Miller WG, Ruffen D, Zhang D: Analytic and clinical performance of two compact cholesterol-testing devices. Pharmocotherapy.18: 184-92, 1998. CR - Stein JH, Carlsson CM, papeke-benson K, Einerson JA, McBride PE, Wiebe DA: Inaccuracy of lipid measurements with the portable Cholestech LDX analyzer in patients with hypercholesterolemia. Clin Chem. 48:284-90, 2002. UR - https://dergipark.org.tr/en/pub/dtfd/article/610915 L1 - https://dergipark.org.tr/en/download/article-file/793143 ER -