@article{article_615442, title={Improved Clinical Outcomes After Arthroscopic Microfracture in Isolated Medial Talar Osteochondral Lesions with a Single Injection of High Molecular Weight Hyaluronic Acid}, journal={Konuralp Medical Journal}, volume={11}, pages={460–467}, year={2019}, author={Arıcan, Mehmet and Değirmenci, Erdem}, keywords={Ankle Injuries,Cartilage,Arthroscopy,Hyaluronic Acid}, abstract={<p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">Objective: </span> </b> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb"> To investigate the efficacy of a single intra-articular injection of
high molecular weight hyaluronic acid (HMW-HA) for treating isolated medial
osteochondral lesions (OCLs) of the talus following <span style="letter-spacing:.1pt;background:#FCFCFC;"> arthroscopic </span> microfracture. </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">Methods: </span> </b> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">A total of 39
patients, treated between 2014–2017 for medial OCLs of the talus, were enrolled in the study. Patients were split
into two groups: group 1, consisting of 18 patients who received a single of 4
ml of HMW-HA (22 mg/ml) injection following microfracture; and group 2,
consisting of 21 patients who underwent microfracture but did not receive an
injection. Functional and clinical outcomes were assessed at baseline, 6
months, and at a final follow-up using a visual analogue scale (VAS) and the </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">American Orthopaedic Foot and
Ankle Society Ankle-Hindfoot Scale </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb"> (AOFAS). </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">Results: </span> </b> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb"> The mean AOFAS score increased in groups 1 and 2, from </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">45.61±14.71 </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">to </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">95.11±5.02 </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb"> (p=0.0001) and </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">41.81±13.83 </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">to </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">90.29±7.43 </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb"> (p=0.0001),
respectively. Similarly, the mean VAS score decreased in groups 1 and 2 from </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">8.72±1.23 </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">to </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">2.11±1.45 </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb"> (p=0.0001) and </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">9.05±0.80 </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb"> to </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb">3.67±2.22 </span> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-gb"> (p=0.0001),
respectively. In addition, the mean AOFAS score in group 1 was higher than in
group 2 (p=0.025) at the final follow-up, and the mean VAS score in group 1 was
lower than that of group 2 (p=0.0001, p=0.015, respectively) at 6 months
postoperatively and the final follow-up. <b> </b> </span> </p> <p> <b> </b> </p> <b> </b> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span lang="en-gb" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;color:#231F20;" xml:lang="en-gb">Conclusions: </span> </b> <span lang="en-gb" xml:lang="en-gb"> </span> <span}, number={3}, publisher={Duzce University}