@article{article_626510, title={Investigation of The Effect of Intermediate Dose Calculation Module on Dose Dıstrıbutıon in Lung Cancer Radiotherapy Patients}, journal={International Journal of Computational and Experimental Science and Engineering}, volume={5}, pages={142–146}, year={2019}, DOI={10.22399/ijcesen.626510}, author={Yahşi Çelen, Yonca and Kızılkaya, Hazım Orhan}, keywords={Lung Cancer,IMRT,Intermediate Dose Calculation,Optimization}, abstract={<p class="MsoNormal" style="text-align:justify;"> <span lang="en" style="color:#222222;" xml:lang="en">The aim of this study was to investigate the effect of the use of intermediate dose calculation module on dose volume histogram (DVH) during dose optimization in the treatment plans of radiotherapy patients diagnosed with lung cancer. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;"> <span lang="en" style="color:#222222;" xml:lang="en">This study was carried out by using Eclipse (Version 15.3) treatment planning system with Trilogy model Linear Accelerator device in Radiation Oncology Department of Şişli Hamidiye Etfal Training and Research Hospital. Ten patients with lung cancer were included in the study. In this study, critical organ doses, conformity index (CI) and homogenity index (HI) were compared by making optimization in cases where intermediate dose calculation module was active and inactive. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;"> <span lang="en" style="color:#222222;" xml:lang="en">The plans using the Intermediate dose calculation model are more homogeneous and uniform. Differences between critical organ doses, conformity index (CI) and homogenity index (HI) were statistically significant when using the Intermediate dose calculation module. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;"> <span lang="en" style="color:#222222;" xml:lang="en">It has been demonstrated that the intermediate dose calculation method in heterogeneous lung cancer patients is superior in terms of dose homogeneity and tumor volume enveloping, which improves the quality of treatment plans. </span> <span style="color:#222222;"> </span> </p> <p> </p>}, number={3}, publisher={İskender AKKURT}