TY - JOUR T1 - Investigation of The Effect of Intermediate Dose Calculation Module on Dose Dıstrıbutıon in Lung Cancer Radiotherapy Patients AU - Yahşi Çelen, Yonca AU - Kızılkaya, Hazım Orhan PY - 2019 DA - November Y2 - 2019 DO - 10.22399/ijcesen.626510 JF - International Journal of Computational and Experimental Science and Engineering JO - IJCESEN PB - İskender AKKURT WT - DergiPark SN - 2149-9144 SP - 142 EP - 146 VL - 5 IS - 3 LA - en AB - The aim of this study was toinvestigate the effect of the use of intermediate dose calculation module ondose volume histogram (DVH) during dose optimization in the treatment plans ofradiotherapy patients diagnosed with lung cancer.This study was carried out by usingEclipse (Version 15.3) treatment planning system with Trilogy model LinearAccelerator device in Radiation Oncology Department of Şişli Hamidiye EtfalTraining and Research Hospital. Ten patients with lung cancer were included inthe study. In this study, critical organ doses, conformity index (CI) andhomogenity index (HI) were compared by making optimization in cases whereintermediate dose calculation module was active and inactive.The plans using the Intermediatedose calculation model are more homogeneous and uniform. Differences betweencritical organ doses, conformity index (CI) and homogenity index (HI) werestatistically significant when using the Intermediate dose calculation module.It has been demonstrated that theintermediate dose calculation method in heterogeneous lung cancer patients issuperior in terms of dose homogeneity and tumor volume enveloping, whichimproves the quality of treatment plans. KW - Lung Cancer KW - IMRT KW - Intermediate Dose Calculation KW - Optimization CR - [1] S.G. Spiro, J.C. Porter; “Lung cancer-Where are we today? Current advances in staging and nonsurgical treatment” Am J Respir Crit Care Med. 166:1166–1196. (2002). CR - [2] G.M. Parkin, P. Pisani, J. 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