TY  - JOUR
T1  - Analysis of patients admitted to the emergency service for warfarin complication and determination of their levels of knowledge and requirements of knowledge about warfarin use
AU  - Duman, Ali
AU  - Akoz, Ayhan
AU  - Dagli, Bekir
AU  - Kapci, Mucahit
AU  - Avcil, Mucahit
AU  - Ozdemir, Ferdi
PY  - 2019
DA  - October
Y2  - 2016
JF  - Deneysel ve Klinik Tıp Dergisi
JO  - J. Exp. Clin. Med.
PB  - Ondokuz Mayıs University
WT  - DergiPark
SN  - 1309-4483
SP  - 247
EP  - 250
VL  - 34
IS  - 4
LA  - en
AB  - Warfarin is a cumarol derivative anticoagulant. It shows its effect by antagoniz-ing the effects of Vitamin K. Warfarin is metabolized in the liver. Internationalnormalized ratio has been developed in the monitorization of warfarin. It is adrug which has a limited therapeutic index. The difference in sensitivity fortherapy dose among individuals depends on the genetic polymorphism of thetwo enzymes in the liver. The objective of our study was to assess the informa-tion about the demographic characteristics, complications, treatments and therelated factors of the patients who were admitted to our emergency service forhigh INR in routine controls and of the cases who had bleeding due to warfarinoverdose. Of the 18-year-old and older patients who were admitted to our emer-gency service with a complaint related to warfarin use and who had been usingwarfarin on admission and patients who had an INR value of over 3.0 althoughthe patient had no complaints, those who accepted to participate in the studywere included in the study. The results of the demographic characteristics, com-plications and treatments of the 59 patients included in the study were in paral-lel with the literature. The rate of patients’ being informed was found as 61%.Although difference was found when the demographic data of the informed andnon-informed groups and their answers to the questions asked for warfarin in-formation level were compared, no statistically significant difference was found(p>0.005). This brings to mind that the information given to patients at the timeof first prescription is not sufficient and it does not turn into a regular training. 
KW  - Drug information
KW  - Emergency Service
KW  - Warfarin
KW  - Warfarin complication
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UR  - https://dergipark.org.tr/en/pub/omujecm/issue//628851
L1  - https://dergipark.org.tr/en/download/article-file/827836
ER  -