@article{article_629692, title={SYNTHESIS OF OPEN-CHAIN SUGAR DERIVATIVES AS ANTICANCER AND ANTIMICROBIAL AGENTS}, journal={Communications Faculty of Sciences University of Ankara Series C Biology}, volume={28}, pages={148–159}, year={2019}, author={Yazgan, İdris}, keywords={Carbohydrate derivatives,lectins,Anticancer,Antibacteri}, abstract={<p class="MsoHeader" style="margin-top:0cm;margin-right:35.55pt;margin-bottom:.0001pt;margin-left:31.5pt;text-align:justify;"> <span lang="en-us" style="font-size:8pt;" xml:lang="en-us">In the present study, three sugar residues
including mannose, galactose and lactose were modified with organic
substituents via reductive amination reaction in order to get strong anticancer
carbohydrate derivatives for A549 cell line and antibacterial agents targeting <i>E.coli </i> and <i>S.epidermidis </i>. The findings showed that carbohydrate residue along
with substituted group play the major role for the observed activity of the
carbohydrate ligands. </span> <span lang="en-us" style="font-size:9pt;" xml:lang="en-us"> </span> </p> <p> </p>}, number={2}, publisher={Ankara University}, organization={Kastamonu Üniversitesi}