@article{article_637170, title={The relationship between angiotensin converting enzyme gene polimorphism and lacunar infarction}, journal={Harran Üniversitesi Tıp Fakültesi Dergisi}, volume={10}, pages={131–136}, year={2013}, author={Akar, Handan and Cengiz, Nilgün and Bedir, Abdülkerim and Onar, Musa Kazım}, keywords={Lacunar infarction,ACE gene polymorphism,genetic}, abstract={Background: To evaluate the relationship between polymorphisms of the angiotensin converting enzyme ACE gene and cerebral lacunar infarction.Methods: We included 23 patients with cerebral lacunar infarct confirmed with computerized tomography CT , and 26 controls with normal CT scans. We considered age, sex, hypertension, diabetes mellitus, cardiac disease, hyperlipidemia and smoking as risk factors. Insertions or deletions I/D in the ACE gene were detected using polymerase chain reaction PCR .Results: The average incidence of hyperlipidemia and mean age were higher in the lacunar infarct group p}, number={3}, publisher={Harran University}