TY - JOUR T1 - Bilateral ve tekrarlayan fasiyal paralizinin nadir nedeni: Melkersson-Rosenthal sendromu AU - Akdağ, Mehmet AU - Özkurt, Fazıl AU - Yılmaz, Beyhan AU - Topçu, İsmail AU - Meriç, Faruk PY - 2015 DA - May DO - 10.5798/diclemedj.0921.2015.01.0541 JF - Dicle Medical Journal JO - diclemedj PB - Dicle University WT - DergiPark SN - 1300-2945 SP - 102 EP - 106 VL - 42 IS - 1 LA - tr AB - Melkersson-Rosenthal Sendromu yineleyen periferik fasiyal paralizi, orofasiyal ödem ve fissürlü dil triadı ile karakterize granülomatöz hastalıktır. Bu yazımızda çocukluktan itibaren 2 kez sol ve bir kez sağ taraftan periferik paralizi atağı geçiren ve idiopatik fasiyal paralizi tanısı alan olgunın kliniğimize tekrar sağ tarafta periferik fasiyal paralizi ön tanısı ile yatırılıp tetkik ve takip sonucunda Melkersson-Rosenthal Sendromu (MRS) tanısı alan hastada; fasiyal paralizinin farklı tarafta ve farklı zamanlarda tekrarlayıcı olması ve tedaviye dirençli olması ve ayrıca gençlik çağında ender görülüyor olması nedeniyle sunulmuştur. Ancak bu sendromla ilgili gerek doğru etiyoloji ve gerekse sonuç veren tedavi açısından klinikopatolojik ek çalışmalara ihtiyaç duyulmaktadır. Anahtar kelimeler: Melkersson-rosenthal sendromu, fasiyal paralizi, fissürlü dil KW - Melkersson-rosenthal sendromu KW - fasiyal paralizi KW - fissürlü dil N2 - Melkersson-Rosenthal syndrome is a granulomatous disease which is characterized by the triad of recurrent peripheral facial palsy, orofacial edema, and fissured tongue. In this article we presented one case who, since childhood, had had peripheral paralysis attack twice on the left side and once in the right side and was diagnosed with idiopathic paralysis before being admitted to our clinic for the second time with the preliminary diagnosis of peripheral facial paralysis on the right side and then diagnosed and followed up with the diagnosis of Melkersson-Rosenthal Syndrome (MRS). We presented this case since the facial paralysis recurred on the different side and in different times and also since it remained resistant to treatment of steroids and it is seen rarely in adolescence. However, further clinic-pathological studies are required to investigate the etiology and find right treatment procedures for this syndrome CR - Zimmer WM, Rogers RS, Reeve CM, et al. Orofacial manifestations CR - of Melkersson-Rosenthal syndrome. A study of CR - patients and review of 220 cases from the literature. Oral CR - Surg Oral Med Oral Pathol 1992;74: 610-619. CR - Ziem PE, Pfrommer C, Goerdt S, et al. Melkersson-Rosenthal CR - syndrome in childhood: a challenge in differential diagnosis CR - and treatment. Br J Dermatol 2000; 143:860-863. CR - Armstrong DK, Burrows D. Orofacial granulomatosis. Int J CR - Dermatol 1995;34:830-833. CR - Worsaae N, Christensen KC, Schiodt M, et al. MRS and cheilitis CR - granulomatosa. A clinicopathological study of thirty CR - three patients with special reference to their oral lesions. CR - Oral Surg Oral Med Oral Pathol 1982;54:404-413. CR - Greene RM, Rogers RS. MRS: a review of 36 patients. J Am CR - Acad Dermatol 1989;21:1263-1270. CR - Cockerham KP, Hidayat AA, Cockerham GC, et al. Melkersson-Rosenthal syndrome: new clinicopathologic findings in 4 cases. Arch Ophthalmol 2000;118:227-232. CR - Wong GA, Shear NH. Melkersson-Rosenthal syndrome associated CR - with allergic contact dermatitis from octyl and dodecyl CR - gallates. Contact Dermatitis 2003;49:266-267. CR - Camacho-Alonso F, Bermejo-Fenoll A, Lopez-Jornet P. CR - Miescher’s cheilitis granulomatosa. A presentation of five CR - cases. Med Oral Patol Oral Cir Buccal 2004;9:427-429. CR - Rogers RS 3rd. Melkersson-Rosenthal syndrome and orofacial CR - granulomatosis. Dermatol Clin 1996;14:371-379. CR - May M, Klein SR. Differrential diagnosis of facial nerve CR - palsy. Otolaryngol Clin North Am 1991;24:613-645. CR - Cockerham KP, Hidayat AA, Cockerham GC, et al. Melkersson-Rosenthal syndrome: new clinicopathologic findings in 4 cases. Arch Ophthalmol 2000;118:227-232. CR - Perez-Calderon R, Gonzalo-Garijo MA, Chaves A, et al. CR - Cheilitis granulomatosa of Melkersson-Rosenthal syndrome: CR - treatment with intralesional corticosteroid injections. CR - Allergol Immunopathol 2004;32:36-38. CR - Kruse-Losler B, Presser D, Metze D, et al. Surgical treatment CR - of persistent macrocheilia in patients with Melkersson-Rosenthal CR - syndrome and cheilitis granulomatosa. Arch CR - Dermatol 2005;141:1085-1091. CR - Özdemir HH, Demir CF, M. Berilgen S, ve ark. Gebelik ve CR - fasiyal dipleji: Nadir bir olgu. Dicle Med J 2012;39:419-421. UR - https://doi.org/10.5798/diclemedj.0921.2015.01.0541 L1 - https://dergipark.org.tr/en/download/article-file/54543 ER -