TY  - JOUR
T1  - Anti-TNF tedavi seyrinde gelişen otoimmün hastalıklar: Eşlik eden hastalık mı? İlaca mı bağlı?
TT  - Autoimmune diseases during anti-TNF therapy: Coexisting disease? Drug-induced?
AU  - Çelik, Selda
PY  - 2019
DA  - October
DO  - 10.19161/etd.648470
JF  - Ege Journal of Medicine
JO  - EJM
PB  - Ege University
WT  - DergiPark
SN  - 1016-9113
SP  - 8
EP  - 10
LA  - tr
AB  - Anti-TNF tedavilerin romatolojik ve otoimmün hastalıkların tedavisinde yaygın kullanımı ve uzun dönem takipleri ile birlikte, paradoksal olarak anti-TNF ilişkili otoimmün hastalıklarla ilgili artan sayıda bildiriler olmaktadır. Bu ilaçlar genelde ağır hastalık aktivitesi olan romatolojik hastalarda kullanıldığından, bazı durumlarda bu gelişen hastalıkların altta yatan hastalığa da bağlı olabilmesi ile ilgili çelişkiler bulunmaktadır. Giderek artan vaka serilerinden elde edilen bilgiler ışığında bu konuyu tartışmayı amaçladık
KW  - Anti-TNF tedavi
KW  - otoimmün hastalık
KW  - vaskülit
KW  - sistemik lupus eritematoz
N2  - Tumor necrosis factor (TNF)-targeted therapies are increasingly used for a rapidly expanding number of rheumatic and autoimmune diseases. With this use and longer follow-up periods of treatment, there are a growing number of reports of the development of autoimmune processes related to anti-TNF agents. Since these drugs are often prescribed to severe rheumatologic patients, there is a controversy about whether the autoimmune diseases that could be related to underlying disease or anti-TNF therapy. We aimed to discuss this subject under the light of literature.
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UR  - https://doi.org/10.19161/etd.648470
L1  - https://dergipark.org.tr/en/download/article-file/857816
ER  -