@article{article_655007, title={Usefulness of Serum Brain Natriuretic Peptide as a Predictor Biomarker of Renal Artery Stenosis in Patients with Resistant Hypertension}, journal={Turkish Journal of Diabetes and Obesity}, volume={3}, pages={155–163}, year={2019}, author={Uygun İlikhan, Sevil and Bilici, Muammer}, keywords={Brain natriuretic peptid,renal artery stenosis,resistant hypertension}, abstract={<div style="text-align:justify;"> <span style="font-size:12px;">Aim: In this study, we aimed to evaluate the relationship between BNP level and RAS in patients with resistant hypertension according  </span> <span style="font-size:12px;">to the results of renal arteriography.    </span> </div> <div style="text-align:justify;"> <br /> </div> <div style="text-align:justify;"> <span style="font-size:12px;">Material and Methods: Forty patients with resistant hypertension were included to the study. In order to compare to each other  </span> <span style="font-size:12px;">regarding the BNP levels, the patients were evaluated by dividing them into groups as RAS (group1; non-critical (1a) and critical (1b)),  </span> <span style="font-size:12px;">non-RAS (group 2), unilateral RAS (non-critical (A) and critical (B)) and bilateral RAS (non-critical (C) and critical (D)) according to  </span> <span style="font-size:12px;">the results of renal arteriography.   </span> </div> <div style="text-align:justify;"> <br /> </div> <div style="text-align:justify;"> <span style="font-size:12px;">Results: The serum BNP (p=0.003) and serum creatinine (p=0.015) levels of group 1b were also significantly higher than group 1a. The  </span> <span style="font-size:12px;">patients in group B had higher serum BNP levels (p=0.025) and lower creatinine clearance levels (p=0.041) compared to group A. Higher  </span> <span style="font-size:12px;">serum creatinine (p=0.006), serum BNP levels (p=0.017) and lower creatinine clearance levels (p=0.049) have been observed in group  </span> <span style="font-size:12px;">D compared to group C.   </span> </div> <div style="text-align:justify;"> <br /> </div> <div style="text-align:justify;"> <span style="font-size:12px;">Conclusion: Findings of this study revealed that increased serum BNP levels were significantly associated with the severity of RAS  </span> <span style="font-size:12px;">determined by the results of renal arteriography. Thus BNP may be used as a predictive marker to detect the presence of RAS in patients  </span> <span style="font-size:12px;">with resistant hypertension.  </span> </div>}, number={3}, publisher={Zonguldak Bulent Ecevit University}