TY  - JOUR
T1  - Characterization, Identification and Phylogeny of the Creatine Kinase (ckma) Gene in Medaka (Oryzias latipes)
AU  - Bayır, Mehtap
AU  - Arslan, Gökhan
AU  - Oğuzhan Yıldız, Pinar
PY  - 2020
DA  - June
Y2  - 2020
DO  - 10.33714/masteb.660220
JF  - Marine Science and Technology Bulletin
JO  - Mar. Sci. Tech. Bull.
PB  - Adem Yavuz SÖNMEZ
WT  - DergiPark
SN  - 2147-9666
SP  - 15
EP  - 22
VL  - 9
IS  - 1
LA  - en
AB  - Creatine kinase (ckma) has been characterized and described inthe medaka (Oryzias latipes), an aquatic model organism and the genestructure has been designed using the exons, introns, produced amino acids ofthe gene, TATA box, poly A tail and 5’ UTR and 3’ UTR regions of the ckmagene. In another step, firstly, the chromosome region of the ckma genewas determined in medaka and then the other genes which placed in the sameregion were determined. Then the locations of these genes were determined inzebrafish and human which are the orthologs of medaka. Finally, the conservedgene synteny was designed manually, using these data. However, genetic identityand similarity ratio between medaka and its orthologs were calculated. In thisstudy, characterization and identification, phylogenetic relationship,conserved gene synteny of ckma gene in medaka (O. latipes) whichis an important model organism were analyzed by using bioinformatics tools(NCBI database, Ensembl genomic database, Expasy, Reverse Complementary andsome programs such as MEGA6 program, BLOSUM62 matrix program and BioEditsoftware). All these data will be used in future studies on molecular stressresponse in fish and they were presented to the scientific world with thisstudy.
KW  - Medaka
KW  - Genomic organization
KW  - Model organism
KW  - Bioinformatics
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UR  - https://doi.org/10.33714/masteb.660220
L1  - https://dergipark.org.tr/en/download/article-file/955148
ER  -