TY  - JOUR
TT  - Effects of Thymoquinone on Oxidative Stress in the Testicular  Tissue of Reserpinized Rats
AU  - Kuzay, Dilek
PY  - 2019
DA  - December
DO  - 10.5798/dicletip.661402
JF  - Dicle Medical Journal
JO  - diclemedj
PB  - Dicle University
WT  - DergiPark
SN  - 1300-2945
SP  - 831
EP  - 837
VL  - 46
IS  - 4
LA  - en
KW  - Reserpine; Oxidative stress; Rats; Testis; Thymoquinone
N2  - Objective: The objective of the study was to  research the oxidant and antioxidant activity of Thymoquinone (TQ) inthe testicular tissue of Reserpinized rats.  Methods: Eighteen rats were divided into three groups and each group had six animals: 1) Control (C) group: Receivedip. 1% Tween 80; 2) Reserpine (R) group: Received Reserpine; 3) Reserpine + TQ (R+T) group: Received Reserpineand TQ. Reserpine was injected intraperitoneally 0.2 mg/kg and TQ was administered intragastrically 10 mg/kg oncedaily. The rats were treated for 14 consecutive days. At the end of the study, total nitric oxide (NOx) levels,malondialdehyde (MDA) levels and glutathione (GSH) levels in the testicular tissue were examined. Results: A statistically significant increase was observed in the NOx levels (p=0.001) and MDA levels of testiculartissue in the R group (p
CR  - 1. Erdemir F, Atilgan D, Firat F, et al. The effect of
Sertraline, Paroxetine, Fluoxetine and Escitalopram on
testicular tissue and oxidative stres parameters in rats.
Int Braz J Urol. 2014; 40: 100-8.
UR  - https://doi.org/10.5798/dicletip.661402
L1  - https://dergipark.org.tr/en/download/article-file/891715
ER  -