TY - JOUR T1 - Ege Üniversitesi Hastanesinde renal kanser hastalarının epidemiyolojisi ve genel sağ kalım özellikleri TT - Epidemiological and overall survival characteristics of kidney cancer patients in Ege University Hospital database AU - Gürsoy, Pınar AU - Çakar, Burcu AU - Gökmen, Erhan AU - Sarsık Kumbaracı, Banu AU - Şen, Sait AU - Apaydın, Erdal AU - Çal, A. Çağ AU - Caner, Ayse AU - Özkök, Serdar AU - Haydaroğlu, Ayfer PY - 2019 DA - December DO - 10.19161/etd.669480 JF - Ege Tıp Dergisi JO - EJM PB - Ege University WT - DergiPark SN - 1016-9113 SP - 133 EP - 139 LA - tr AB - Amaç: Ege Üniversitesi Hastanesinde 1992-Haziran 2018 arası kanser tanısı konan ve tedavisiyapılan renal kanser tanılı hastaların genel özellikleri, tedavi modaliteleri ve sağ kalım sürelerinintanımlanması amaçlanmıştır.Gereç ve Yöntem: Ege Üniversitesi Kanserle Savaş Araştırma ve Uygulama Merkezi tarafındantoplanan renal kanser verileri CANREG özel bilgisayar programına kayıt edilmiş, DSÖ ve SEERsistemleri temelinde gruplanarak analizler yapılmıştır. İstatistik analizlerde Fisher’s Exact Test,KaplanMeier sağ kalım analizleri uygulanmıştır. Sağ kalım analizinde Log Rank (Mantel-Cox), Breslow(Generalized Wilcoxon) ve Tarone-Ware istatistikleri kullanılmıştır. İstatistik analizlerde p KW - Böbrek kanseri KW - epidemiyoloji KW - insidans KW - genel sağ kalım. N2 - Aim: The purpose of this study was to describe the general characteristics, treatment modalities andoverall survival times of kidney cancer patients that diagnosed and treated in between 1992 –andJune 2018 at Ege University Hospital.Materials and Methods: Ege University Cancer Control, Research and Application Centerregistered the collected kidney cancer data in CANREG which is a special computer program forgrouping and analyzing the data in WHO and SEER based systems. Fisher’s Exact Test KaplanMeier survival analyzing technique was used in statistical analysis. Log Rank(Mantel-Cox),Breslow(Generalized Wilcoxon) and Tarone-Ware statistical techniques were used in survivalanalysis. P CR - SEER Stat Fact Sheets: Kidney and Renal Pelvis. http://seer.cancer.gov/statfacts/html/kidrp.html . CR - Störkel S,van den Berg E. Morphological classification of renal cancer. World J Urol. 1995;13(3):153-8. CR - Israel GM, Bosniak MA. How I do it: evaluating renal masses. Radiology, 236 (2), 441-50. CR - Johnson CD, Dunnick NR, Cohan RH, Illescas FF. Renal adenocarcinoma: CT staging of 100 tumors. AJR Am J Roentgenol, 148 (1), 59-63. CR - Koga S, Tsuda S, Nishikido M et al. The diagnostic value of bone scan in patients with renal cell carcinoma. J Urol, 166 (6), 2126-8. CR - Ramdave S, Thomas GW, Berlangieri SU et al.Clinical role of F-18 fluorodeoxyglucose positron emission tomography for detection and management of renal cell carcinoma. J Urol. 2001 Sep;166(3):825-30. CR - Novara G, Martignoni G, Artibani W, Ficarra V. Grading systems in renal cell carcinoma. J Urol. 2007 Feb;177(2):430-6. CR - Cheville JC, Lohse CM, Zincke H et al. Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma. Am J Surg Pathol. 2003 May;27(5):612-24. CR - Kassouf W, Sanchez-Ortiz R, Tamboli P et al. Cytoreductive nephrectomy for metastatic renal cell carcinoma with nonclear cell histology. . J Urol. 2007 Nov;178(5):1896-900. Epub 2007 Sep 17. CR - Motzer RJ, Hutson TE, Tomczak P et al. Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol. 2009 Aug 1;27(22):3584-90. doi: 10.1200/JCO.2008.20.1293. Epub 2009 Jun 1. CR - Rini BI, Halabi S, Rosenberg JE et al. Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206. . J Clin Oncol. 2010 May 1;28(13):2137-43. doi: 10.1200/JCO.2009.26.5561. Epub 2010 Apr 5. UR - https://doi.org/10.19161/etd.669480 L1 - https://dergipark.org.tr/en/download/article-file/915954 ER -