@article{article_681819, title={Increased DNA Damage of Radiology Personnel Chronically Exposed to Low Levels of Ionizing Radiations}, journal={Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi}, volume={11}, pages={212–216}, year={2020}, DOI={10.22312/sdusbed.681819}, author={Toğay, Vehbi Atahan and Yıldırım Baş, Funda and Aşcı Çelik, Dilek and Özçelik, Nurten and Yavuz Türel, Gülçin and Calapoğlu, Mustafa and Aslan Kosar, Pinar}, keywords={Ionizing radiation,Comet assay,DNA damage,Radiology personnel}, abstract={<p class="Body" style="text-align:justify;line-height:150%;"> <b> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Objective: </span> </b> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us">
Occupational life has a direct relation with health. People working in the
hospital units such as Radiology and Nuclear Medicine are subject to higher
doses of ionizing radiation than ordinary person. We examined the association
between DNA damage and ionizing radiation exposure in the personnel working in
university hospital and considered different variables such as smoking, age
etc. <b>Material - Method: </b> DNA Damage
levels were estimated via comet assay in peripheral lymphocytes from 48 exposed
and from 51 non-exposed subjects, aged between 18-57 years old. Tail DNA
percentage parameter, obtained through Open Comet program, was chosen to assess
DNA damage and the results were evaluated by the One - Way Anova statistical test. <b>Results: </b> The results, obtained from
statistical comparison of tail DNA percentage parameter, indicate that even the
low dose radiation caused DNA damage and age, gender, smoking habits and
working years did not show any significant differences except for dosimetry
value. Increasing dosimetry value resulted in increased DNA damage. <b>Conclusion: </b> This work supports the
previous results of biomonitoring of radiology workers chronically exposed to
ionizing radiation. This means ionizing radiation is still an important DNA
damaging agent despite many improvements such as exposed time reduction,
working conditions and technology. </span> </p> <p> </p> <p> </p>}, number={2}, publisher={Süleyman Demirel University}, organization={Süleyman Demirel Üniversitesi (ÖYP)}