@article{article_683602, title={The Paradigm of Autoimmunity: Is Vitamin D the New Player?}, journal={Maltepe Tıp Dergisi}, volume={8}, pages={1–6}, year={2016}, author={Sezgin, Gülbüz and Özer, Eşref M. and Bayramiçli, Oya Uygur and Akgün, Feride Sinem and Aksungar, Fehime Benli and Nalbant, Selim}, keywords={nazolabiyal,V-Y ilerletme flebi,ortayüz defekti,ektropiyon}, abstract={Aim: Vitamin D is necessary for the bone and mineral homeostasis and has also immune regulatory and anti-inflammatory functions. It has been hypothesized that there is a relation between vitamin D deficiency or insufficiency and autoimmune thyroiditis. We aim that to show any relationship between vitamin D deficiency and thyroid autoimmunity. Material and Methods: This prospective study is performed between August 2010 and May 2011 at the Department of Internal Medicine, Endocrinology and Emergency Medicine of Maltepe University, School pof Medicine Hospital. The Ethics Committee of Maltepe University Medical Faculty approved the study.274 patients with Hashimoto’s thyroiditiswere evaluated prospectively for vitamin D, TSH, anti-thyroid peroxidase antibody anti-TPO and anti-thyroglobulin anti-Tg .The correlation between vitamin D and autoimmune parameters is analyzed. Results: According to vitamin D levels there is a statistically significant difference between anti- TPO levels p=0.024; p0.05 . There is also no difference in TSH levels according to vitamin D subgroups p=0.177; p>0.05 . Conclusion: In patients with Hashimoto’s thyroiditis there is a positive correlation between vitamin D level and anti-TPO but not anti-Tg.}, number={2}, publisher={Maltepe University}