TY - JOUR T1 - Böbrek hücreli kanserde yaş ve cinsiyetin sağkalım üzerine etkisi TT - The effect of age and gender on survival in renal cell carcinoma AU - Görgel, Sacit Nuri AU - Özer, Kutan AU - Köse, Osman AU - Yılmaz, Yüksel AU - Horsanalı, Ozan PY - 2015 DA - January JF - Yeni Üroloji Dergisi JO - New J Urol. PB - Ali İhsan TAŞÇI WT - DergiPark SN - 1305-2489 SP - 6 EP - 11 VL - 10 IS - 1 LA - tr AB - Amaç: Radikal nefrektomi yapılan hastalarda yaş ve cinsiyetin sağ kalıma etkisini araştırmak. Gereç ve Yöntemler: 1990 – 2012 tarihleri arasında kliniğimizde böbrek tümörü nedeniyle radikal nefrektomi operasyonu uygulanan 177 hasta retrospektif olarak değerlendirildi. Hastalar yaş gruplarına göre 5 gruba KW - Böbrek tümörü KW - cinsi N2 - Objective: To evaluate the effect of age and gender on survival in patients who underwent radical nephrectomy. Materials and Methods: A hundred and seventy seven patients who underwent radical retrospectively because of renal carcinoma were eveluated retrosepectively between 1990 and 2012. Patients are divided into five groups CR - Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin 2011;61:69-90. CR - Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 2010;46:765-81. CR - Lindblad P. Epidemiology of renal cell carcinoma. Scand J Surg 2004;93:88-96. CR - Ferlay J, Bray F, Forman D, et al. GLOBOCAN 2008 v1.2, Cancer Incidence and MortalityWorldwide: IARC Cancer- Base No. 10 2010, International Agency for Research on Cancer:Lyon,France. CR - Kovacs G, Akhtar M, Beckwith BJ, et al. The Heidelberg classification of renal cell tumours. J Pathol 1997;183:131- 3. CR - Lipworth L, Tarone RE, McLaughlin JK. The epidemiology of renal cell carcinoma. J Urol 2006;176:2353-8. CR - Bergstrom A, Hsieh CC, Lindblad P, et al. Obesity and renal cell cancer-a quantitative review. Br J Cancer 2001;85:984- 90. CR - Pischon T, Lahmann PH, Boeing H, et al. Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition EPIC. Int J Cancer 2006;118:728-38 CR - Weikert S, Boeing H, Pischon T, et al. Blood pressure and risk of renal cell carcinoma in the European prospective investigation into cancer and nutrition. Am J Epidemiol 2008;167:438-46. CR - Waalkes S, Merseburger AS, Kramer MW, et al. Obesity is associated with improved survival in patients with organ- confined clear-cell kidney cancer. Cancer Causes Control 2010;21:1905-10. CR - Clague J, Lin J, Cassidy A, et al. Family history and risk of renal cell carcinoma: results from a case control study and systematic meta-analysis. Cancer Epidemiol Biomarkers Prev 2009;18:801-7. CR - Gudbjartsson T, Jónasdóttir T.J, Thoroddsen A, et al. A population-based familial aggregation analysis indicates genetic contribution in a majority of renal cell carcinomas. Int J Cancer 2002;100:476-9. CR - Patard JJ, Rodriguez A, Rioux-Leclercq N, et al. Prognos- tic significance of the mode of detection in renal tumours. BJU Int 2002;90:358-63. CR - Kato M, Suzuki T, Suzuki Y, et al. Natural history of small renal cell carcinoma: evaluation of growth rate, histological grade, cell proliferation and apoptosis. J Urol 2004;172:863-6. CR - Tsui KH, Shvarts O, Smith RB, et al. Renal cell carcinoma: prognostic significance of incidentally detected tumors. J Urol 2000;163:426-30. CR - Jung EJ, Lee HJ, Kwak C,et al. Young age is independent prognostic factor for cancer-specific survival of low-stage clear cell renal cell carcinoma. Urology 2009;73:137-41. CR - Denzinger S, Otto W, Burger M,et al. Sporadic renal cell carcinoma in young and elderly patients: are there different clinicopathological features and disease specific survival rates?. World J Urol 2013;31:1073-80. CR - Lee L.S, Yuen J.S.P, Sim H.G. Renal cell carcinoma in yo- ung patients is associated with poorer prognosis. Annals Academy of Medicine 2011;40:401-406. CR - Thompson R.H, Ordonez M.A, Iasones A, et al. Renal cell carsinoma in young and old patient-is there a difference? Urologe A 2008;47:1182-1186. CR - Karakiewicz P.T, Jeldres C, Suardi N, et al. Age at diag- nosis is determinant factor of renal cell carcinoma-spe- sific survival in patients treatedwith nephrectomy. J urol 2008;180:1262-1266. CR - Sangchul J, Hwang G.J, Cheol K. et al. Gender-specific clinicopathological features and survival in patients with renal cell carcinoma RCC. BJU int 2011;110:28-33. CR - Edward N. R, Tobias K, Geoffrey B. et al. The effect of gen- der and age on kidney cancer survival: Younger age is an indipendent prognostic factor in women with renal cell carcinoma. Urologic Oncology 2013;1-5. CR - Schrader A.J, Sevinç S, Olbert P.J.et al. Gender specific cha- racteristics and survival of renal cell carcinoma. Urologe 2008;47:1182-1186. CR - Onishi T, Oishi H, Goto H.et al. Gender as a prognostic factor in patients with renal cell carcinoma. BJU int 2002; 90:32-36. CR - Aron M, Nguyen M.M, Stein R.J, et.al. Impact of gender in renal cell carcinoma: an analysis of the SEER database. Eur Urol jul 2008;54:13340. UR - https://dergipark.org.tr/en/pub/yud/issue//708050 L1 - https://dergipark.org.tr/en/download/article-file/1018414 ER -