TY  - JOUR
T1  - İnsan Metapnömovirüs’e İnfluenza A Virüsünün Eşlik Ettiği 4.5 Aylık Süt Çocuğunda Alt Solunum Yolu Enfeksiyonu
TT  - Lower Respiratory Tract Infection due to coinfection of Influenza A Virus and Human Metapneumovirus in A 4.5-Month-Old Infant With
AU  - Pala, Ayşegül
AU  - Özdemir, Öner
PY  - 2020
DA  - April
Y2  - 2020
DO  - 10.34084/bshr.714709
JF  - Journal of Biotechnology and Strategic Health Research
JO  - J Biotechnol and Strategic Health Res
PB  - Deneysel, Biyoteknolojik, Klinik ve Stratejik Sağlık Araştırmaları Derneği
WT  - DergiPark
SN  - 2587-1641
SP  - 67
EP  - 71
VL  - 4
IS  - 1
LA  - tr
AB  - Alt solunum yolu enfeksiyonları (ASYE) çoğunlukla respiratuvar sinsisyal virüs (RSV), influenza, parainfluenza, rhinovirüs ve adenovirüs kaynaklıdır. Ancak, son yıllarda bu virüslere ek olarak insan metapnömovirüs (iMPV), parainfluenza 4 ve bocavirüs gibi virüslerinde ASYE’ye sebep olduğu gösterilmiştir. Çocukluk çağında birden fazla virüsün ko-enfeksiyonu ile bronşiolit geliştiği unutulmamalıdır. Bu çalışmamızda, ateş ve öksürük şikâyeti ile hastanemize başvuran 4.5 aylık erkek bir bebekte iki farklı virüsün (iMPV ve influenza A) ko-enfeksiyonu sonucu gelişen bronşiolit olgu sunumu anlatılmıştır.
KW  - human metapnömovirüs
KW  - infleunza A
KW  - koenfeksiyon
KW  - bronşiolit
N2  - Lower respiratory tract infections (LRTI) are mostly caused by respiratory syncytial virus (RSV), influenza, parainfluenza, rhinovirus and adenovirus. In recent years human other viruses such as human metapneumovirus (hMPV), parainfluenza 4 and bocavirus also have been reported to cause LRTI. Coinfection of more than one virus in childhood can develop bronchiolitis in children. In this study, we report a case of bronchiolitis developed by coinfection of hMPV and influenza A viruses in a 4.5-month-old male baby who admitted to our hospital with the fever and cough.
CR  - 1. Pavia AT. Viral infections of the lower respiratory tract: old viruses, new viruses, and the role of diagnosis. Clin Infect Dis. 2011;52(4):S284-9.
CR  - 2. Ozdemir O, Bircan O. Human Metapneumovirus Infection in a Patient with Recurrent Wheezing: Case Report. Istanbul Medical Journal, 2019. 20: p. 261-263.
CR  - 3. Vinci A., Lee PJ, Krilov LR. Human Metapneumovirus Infection. Pediatrics in Review, 2018. 39(12): p. 623.
CR  - 4. Simon A, Manoha C, Müller A, Schildgen O. Human Metapneumovirus and Its Role in Childhood Respiratory Infections. Current Pediatrics Reports, 2014;2(3): p. 156-165.
CR  - 5. Kayıran, SM, Ercin S, Kayıran PG, Eroğlu E, Gümüş T, Gürakan B. A case of pneumonia due to co-infection with two different viruses. SETB, 2017. 51(4): p. 342-345.
CR  - 6. Hilmes MA, Daniel Dunnavant F, Singh SP, Ellis WD, Payne DC, Zhu Y, et al. Chest radiographic features of human metapneumovirus infection in pediatric patients. Pediatr Radiol. 2017;47(13):1745-1750.
CR  - 7. Munoz FM. Seasonal influenza in children: Clinical features and diagnosis. In Mallory GB, Edwards, MS (eds). UpToDate Inc. https://www.uptodate.com/contents/seasonal-influenza-in-children-clinical-features-and-diagnosis (Accessed on January 13, 2020.)
CR  - 8. Esposito S, Daleno C, Prunotto G, Scala A, Tagliabue C, Borzani I, et al. Impact of viral infections in children with community-acquired pneumonia: results of a study of 17 respiratory viruses. Influenza Other Respir Viruses 2013;7:18–26.Pilger DA, Cantarelli VV, Amantea SL, Leistner-Segal S. Detection of human bocavirus and human metapneumovirus by real-time PCR from patients with respiratory symptoms in Southern Brazil. Memórias do Instituto Oswaldo Cruz, 2011. 106: p. 56-60.
CR  - 9. Parsania M, Poopak B, Pouriayevali MH, Haghighi S, Amirkhani A, Nateghian A. Detection of Human Metapneumovirus and Respiratory Syncytial Virus by Real-Time Polymerase Chain Reaction Among Hospitalized Young Children in Iran. Jundishapur J Microbiol. 2016; 9(3): e32974.
CR  - 10. Mizuta K, Abiko C, Aoki Y, Ikeda T, Matsuzaki Y, Itagaki T, et al. Seasonal Patterns of Respiratory Syncytial Virus, Influenza A Virus, Human Metapneumovirus, and Parainfluenza Virus Type 3 Infections on the Basis of Virus Isolation Data between 2004 and 2011 in Yamagata, Japan. Japanese Journal of Infectious Diseases. 2013;66(2):p. 140-145.
CR  - 11. Bosis S, Esposito S, Niesters HG, Crovari P, Osterhaus AD, Principi N. Impact of human metapneumovirus in childhood: comparison with respiratory syncytial virus and influenza viruses. J Med Virol. 2005;75(1):101-4.
CR  - 12. Lin TY, Huang YC, Tsao KC, Huang YL. Human metapneumovirus and community-acquired pneumonia in children. Chang Gung Med J. 2005;28: 683–8.
CR  - 13. Ghattas C, Mossad SB. Fatal human metapneumovirus and influenza B virus coinfection in an allogeneic hematopoietic stem cell transplant recipient. Transpl Infect Dis. 2012;14:e41–3.
UR  - https://doi.org/10.34084/bshr.714709
L1  - https://dergipark.org.tr/en/download/article-file/1087408
ER  -