TY  - JOUR
T1  - The Effect of Neutrophil Lymphocyte Ratio on Prognosis of Ovarian Cancer.
TT  - Nötrofil Lenfosit Oranının Over Kanserinin Prognozuna Etkisi.
AU  - Ekinci, Ferhat
AU  - Erdoğan, Atike Pinar
AU  - Dirican, Ahmet
AU  - Çelik, Cumali
AU  - Eniseler, Emine Bihter
AU  - Almacan, Burcu
AU  - Göksel, Gamze
PY  - 2020
DA  - August
JF  - Türk Jinekolojik Onkoloji Dergisi
JO  - TRSGO Dergisi
PB  - Türk Jinekolojik Onkoloji Derneği
WT  - DergiPark
SN  - 2148-5372
SP  - 13
EP  - 16
VL  - 21
IS  - 3
LA  - en
AB  - Objective: In this study, we planned to investigate the association between neutrophil lymphocyte ratio (NLR) and prognosis in ovarian cancer. Materials And Methods: The data of 84 patients who were followed up at Manisa Celal Bayar University Medical Oncology Clinic between May 2011 and November 2018 were analyzed retrospectively. NLR was calculated by dividing absolute neutrophil count by absolute lymphocyte count. The cut-off value of NLR was 4.2 according to the result of ROC analysis and the patients were divided into two groups as
KW  - Ovarian Cancer
KW  - Neutrophil Lymphocyte Ratio
KW  - Prognosis
N2  - Amaç: Bu çalışmada over kanserinde nötrofil lenfosit oranı (NLR) ile prognoz arasındaki ilişkiyi araştırmayı planladık. Gereç ve Yöntem: Mayıs 2011-Kasım 2018 tarihleri arasında Manisa Celal Bayar Üniversitesi Tıbbi Onkoloji Kliniğinde takip edilen 84 hastanın verileri retrospektif olarak incelendi. NLR, mutlak nötrofil sayısının mutlak lenfosit sayısına bölünmesiyle hesaplanmıştır. ROC analizi sonucuna göre NLR'nin cut-off değeri 4.2 idi ve hastalar 4.2 olarak iki gruba ayrıldı. Bu gruplar genel sağkalım (OS) ve progresyonsuz sağkalım (PFS) oranları açısından karşılaştırıldı. Bulgular: 84 hastanın 71'inde preoperatif nötrofil ve lenfosit değerleri incelendi. Tüm çalışma popülasyonunda OS 20 aydı (% 95 GA: 8,3-31,6, std: 5,9). İki grup arasında OS oranları arasında anlamlı fark yoktu (p: 0.279). NLR'si 4.2'den az olan 47 hastanın (% 66) PFS'si 31 ay, PFS değeri 4.2'den yüksek olan 27 (% 29.2) hastada 21 aydı ve istatistiksel olarak anlamlıydı (p; 0,010). Sonuç: Çalışmamızın sonuçları yüksek tedavi öncesi yüksek NLR'nin over kanseri hastalarında kötü prognoz ile ilişkili olduğunu göstermektedir.
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UR  - https://dergipark.org.tr/en/pub/trsgo/issue//726155
L1  - https://dergipark.org.tr/en/download/article-file/1255614
ER  -