TY  - JOUR
T1  - Effects of Acute Sodium Nitrite and Sodium Nitrate on the Development of Drosophila melanogaster
TT  - Akut Sodyum Nitrat ve Sodyum Nitrit Uygulamasının Drosophila melanogaster’in Gelişimi Üzerine Etkileri
AU  - Atlı, Emel
AU  - Eshraghi, Hadi
AU  - Orhan, Alper
PY  - 2020
DA  - December
Y2  - 2020
DO  - 10.31594/commagene.754697
JF  - Commagene Journal of Biology
JO  - Comm. J. Biol.
PB  - ABADER (Adıyaman Bilimsel Araştırmalar Derneği)
WT  - DergiPark
SN  - 2602-456X
SP  - 96
EP  - 99
VL  - 4
IS  - 2
LA  - en
AB  - Sodium nitrite (NaNO2) and sodium nitrate (NaNO3) are used as food preservatives. In addition to teratogenic, mutagenic, and carcinogenic effects, these products are also thought to have endocrine disrupting effects. This study aimed to investigate the effects of sodium nitrite (NaNO2) and sodium nitrate (NaNO3) on the development of Drosophila melanogaster. Third instar larvae of Canton S strain (wild type) were treated to 25 mM, 50 mM, 75 mM NaNO2, and NaNO3 for 6 hours. The pupation and maturation percentages and times were determined. There was no significant difference in the percentage of pupation and maturation compared to the control group (p>0.05). However, 50 and 75 mM NaNO2 exposures caused developmental delay in both the mean pupation and the mean maturation times (p<0.05). Additionally, it was found that mean maturation time was delayed with 50 and 75 mM NaNO3 exposures (p<0.05).
KW  - pupation
KW  - maturation
KW  - developmental time delay
KW  - Food additives
KW  - Drosophila
N2  - Sodyum nitrit (NaNO2) ve sodyum nitrat (NaNO3) gıda koruyucusu olarak kullanılmaktadır. Teratojenik, mutagenic ve kanserojen etkilere ek olarak, bu ürünlerin endokrin bozucu etkileri de vardır. Bu çalışmada, sodyum nitrit (NaNO2) ve sodyum nitratın (NaNO3) Drosophila melanogaster gelişimi üzerindeki etkileri araştırılmıştır. Yabanıl tip Canton S soyunun üçüncü evre larvalarına, 6 saat boyunca 25 mM, 50 mM, 75 mM NaNO2 ve NaNO3 uygulanmıştır. Pupalaşma ve erginleşme yüzdeleri ve süreleri belirlenmiştir. Pupalaşma ve erginleşme yüzdelerinde kontrol grubuna göre istatistiksel olarak anlamlı bir fark saptanmamıştır (p>0.05). Ancak, 50 ve 75 mM NaNO2 uygulamaları hem ortalama pupalaşma hem de ortalama erginleşme sürelerinde gelişimsel gecikmeye neden olmuştur (p<0.05). Ayrıca ortalama erginleşme süresinin 50 ve 75 mM NaNO3 uygulaması ile ertelendiği saptanmıştır (p<0.05).
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UR  - https://doi.org/10.31594/commagene.754697
L1  - https://dergipark.org.tr/en/download/article-file/1157654
ER  -