TY - JOUR T1 - The Effect of Sex and Age on Cortical Grey and White Matter Volumes of Frontal Lobe AU - Ahmed, Wegdan AU - Osman, Tahir AU - Sahin, Bunyamin AU - Elfaki, Amani PY - 2021 DA - May Y2 - 2021 JF - Deneysel ve Klinik Tıp Dergisi JO - J. Exp. Clin. Med. PB - Ondokuz Mayıs University WT - DergiPark SN - 1309-4483 SP - 227 EP - 234 VL - 38 IS - 3 LA - en AB - Background: Grey matter (GM) of the frontal lobe carries out its complex function such as muscle control, speech, decision making, and self-control; while the white matter (WM) of frontal lobe is a major contributor to human brain enlargement and higher structural connectivity. This study was conducted to assess the effect of sex and age on grey and white matter volumes (GMV and WMV) of the frontal lobe and its gyri in healthy young adult Sudanese. Material and methods: The present study included 139 healthy Sudanese subjects (80 males and 59 females). Participant’s ages were ranging between 20-40 years. T1-weighted MR brain images with thickness 1mm were obtained. MR images of the subjects were analyzed using the automatic segmentation software (BrainSuite). GMV and WMV of frontal lobe and its gyri were estimated using the output data of the process of software. Result: Males had greater GMV and WMV of the frontal lobes (251.18±31.80cm3 and 143.48±22.92cm3, respectively) and most of frontal lobe gyri (P KW - BrainSuite KW - Grey and white matter KW - Frontal lobe CR - Prof. Tahir Osman, Department of Anatomy, Faculty of Medicine, The National Ribat University, Khartoum, Sudan CR - Dr.Amani Elfaki, Departments of Anatomy, Faculty of Medicine, National University, Khartoum, Sudan UR - https://dergipark.org.tr/en/pub/omujecm/issue//774350 L1 - https://dergipark.org.tr/en/download/article-file/1217707 ER -