TY - JOUR T1 - Antioxidant Capacity and Essential Oil Composition of Hypericum thymopsis Boiss. (Hypericaceae) from Turkey AU - Arabaci, Turan AU - Koç, Emine PY - 2021 DA - May Y2 - 2021 DO - 10.15671/hjbc.774575 JF - Hacettepe Journal of Biology and Chemistry JO - HJBC PB - Hacettepe University WT - DergiPark SN - 2687-475X SP - 385 EP - 390 VL - 49 IS - 4 LA - en AB - Antioxidant capacity and essential oil composition of Hypericum thymopsis Boiss. (Hypericaceae), an endemic species, distributed in Turkey was determined. The samples of three different populations were used for the analysis. Antioxidant activities was determined by DPPH method from the leaves and flowers. Essential oil analysis was performed from areal parts of plant by gas chromatography (GC) and GC/mass spectrometry (MS). α-Pinene, spathulenol and limonene are determined as the major components of the essential oils. According to the 50% inhibition (IC50) values (μg/mL) the highest antioxidant values were measured in the methanolic extract of flowers. KW - DPPH KW - Endemic KW - GC/MS KW - Guttiferae CR - Referans 1. S. Aslan, Hypericum L. In: A. Güner, S. Aslan, T. Ekim, M. Vural, M.T. Babaç (Ed), A Checklist of the Flora of Turkey (Vascular Plants), Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını, İstanbul, 2012, 523-530. CR - Referans 2. P.H. Davis (Ed.), Flora of Turkey and the East Aegean Islands, Vol.2, Edinburgh University Press, Edinburgh, 1967, 355-401. CR - Referans 3. M. Koçyiğit, N. Özhatay, Wild Plants Used as Medicinal Purpose in Yalova (Northwest Turkey), Turkish J Pharm Sci, 3(2) (2006) 91-103. CR - Referans 4. G. Bulut, E. Tuzlaci, An ethnobotanical study of medicinal plants in Turgutlu (Manisa-Turkey), Journal of Ethnopharmacology, 149 (2013) 633–647. http://dx.doi.org/10.1016/j.jep.2013.07.016 CR - Referans 5. F. Tetik, S. Civelek, U. Cakilcioglu, Traditional uses of some medicinal plants in Malatya (Turkey), Journal of Ethnopharmacology, 146 (2013) 331–346. http://dx.doi.org/10.1016/j.jep.2012.12.054 CR - Referans 6. E.C. Tatsis, S. Boeren, V. Exarchou, A.N. Troganis, J. Vervoort, I.P. Gerothanassis, Identification of the major constituents of Hypericum perforatum by LC/SPE/NMR and/or LC/MS, Phytochemistry, 68 (2007) 383−393. CR - Referans 7. S.L.Crockett, Essential Oil and Volatile Components of the Genus Hypericum (Hypericaceae), Natural Product Communication, 5(9) (2010) 1493-1506. CR - Referans 8. E.E. Özkan, A. Mat, An overview on Hypericum species of Turkey, Journal of Pharmacognosy and Phytotherapy, 5(3) (2013) 38-46. doi: 10.5897/JPP2013.0260 CR - Referans 9. D.Z. Orčić, N.M. Mimica-Dukić, M.M. Francišković, S.S. Petrović, E.D. Jovin, Antioxidant activity relationship of phenolic compounds in Hypericum perforatum L., Chemistry Central Journal, 5(34) (2011) 1-8. doi:10.1186/1752-153X-5-34 CR - Referans 10. G. Kızıl, M. Kızıl, M. Yavuz, S. Emen, F. Hakimoğlu, Antioxidant Activities of Ethanol Extracts of Hypericum triquetrifolium and Hypericum scabroides, Pharmaceutical Biology, 46(4) (2008) 231–242. doi: 10.1080/13880200701739363 CR - Referans 11. M. Spiteller, T. Ozen, A. Smelcerovic, S. Zuehlke, N. Mimica-Dukic, Phenolic constituents and the in vitro antioxidant activity of the flowers of H. venustum, Fitoterapia, 79(3) (2008) 191-193. CR - Referans 12. T. Arabacı, M.S. İçen, T. Dirmenci, F. Göğer, K.H.C. Başer, Evaluation of Antioxidant Activities, Phenolic Constituents and Essential Oil Composition of Marrubium heterodon (Benth.) Boiss. & Balansa from Turkey, Lat. Am. J. Pharm., 39 (1) (2020) 109-115. CR - Referans 13. W. Brand-Williams, M.E. Cuvelier, C. Berset, Use of free radical method to evaluate antioxidant activity, Lebensm.-Wiss.-u-Technol., 28 (1995) 25-30. CR - Referans 14. A.M.G. Özkan, B. Demirci, K.H.C. Başer. Essential Oil Composition of Hypericum thymopsis Boiss. Journal of Essential Oil Research, 21(2) (2009) 149-153. https://doi.org/10.1080/10412905.2009.9700136 CR - Referans 15. E.E. Özkan, B. Demirci, Ç.Ü. Gürer, Ş. Kültür, A. Mat, K.H.C. Başer, Essential oil composition of five endemic Hypericum species from Turkey, Med. Aromat. Plants, 2(2) (2013) 1000121. DOI: 10.4172/2167-0412.1000121 CR - Referans 16. N. Öztürk, M. Tunçel, İ. Potoğlu-Erkara, Phenolic compounds and antioxidant activities of some Hypericum species: A comparative study with H. perforatum, Pharmaceutical Biology, 47(2) (2009) 120-127. DOI: 10.1080/13880200802437073 UR - https://doi.org/10.15671/hjbc.774575 L1 - https://dergipark.org.tr/en/download/article-file/1218515 ER -