TY - JOUR T1 - Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin ve Linezolid Kombinasyonu: Vaka Sunumu TT - Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report AU - Öcal Demir, Sevliya AU - Atay, Gürkan AU - Kangallı, Özge AU - Kara, Manolya AU - Kaba, Özge AU - Çakar, Emel AU - Durmuş, Mehmet Akif AU - Hançerli Törün, Selda AU - Gökçay, Gülden AU - Gürler, Nezahat AU - Somer, Ayper PY - 2018 DA - July DO - 10.5222/j.child.2018.58224 JF - Çocuk Dergisi PB - Istanbul University WT - DergiPark SN - 1308-8491 SP - 93 EP - 96 VL - 18 IS - 2 LA - tr AB - Linezolid ve vankomisin çok ilaca dirençli Gram pozitif bak- terilerin neden olduğu infeksiyonların tedavisinde günümüz- de başarıyla kullanılmaktadır. Etki spektrumlarının benzerli- ği nedeniyle klasik olarak birlikte kullanılmazlar. Bu maka- lede, ventilatör ilişkili pnömoni ve kateter ilişkili kan akımı infeksiyonu nedeniyle; vankomisin ve linezolid tedavilerinin beraber kullanıldığı ve tedaviye olumlu yanıt alınan bir has- tayı sunduk. Edindiğimiz tecrübe, linezolid tedavisi almakta olan hastada dirençli Gram pozitif bakteriler ile bakteriosta- tik tedavi verilemeyecek kadar ciddi yeni bir infeksiyon geliştiğinde, linezolid ve vankomisin tedavilerini beraber kullanabileceğimiz kanısı oluşturdu KW - Linezolid KW - vankomisin KW - pnömoni N2 - Linezolid and vancomycin have been used successfully in the treatment of infections caused by multidrug resistant gram-positive bacteria. Due to the similarity of the anti- bacterial spectrum, they are not classically used in combi- nation. Herein we present a patient who was successfully treated for catheter-related bloodstream infection and ventilator-associated pneumonia with linezolid and van- comycin combination. 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