@article{article_827893, title={SCRAPIE}, journal={Ankara Üniversitesi Veteriner Fakültesi Dergisi}, volume={11}, year={1964}, DOI={10.1501/Vetfak_0000002069}, author={Zlotnik, I.}, keywords={nervous, septoms, scrapie}, abstract={Scrapie is a progressive disease of sheep characterised by nervous
symptoms and by a diffuse or focal degeneration of the grey matter
of the subcortical centers along the neuroaxis of the central nervous
system. The disease as far as we are aware is invariably fataL.
The clinical symptoms in the shcep consist of incoordination of
gait, trembling and severe itch which causcs persistent rubing of
parts of the body against various fixed objccts. In many cases one
or more of the above symptoms may be cither, diminished or grossly
exaggerated, (Fig. i and 2). .
Apart from an obvious increase in the amount of the cerebrospinal fluid, all other pathological changes are microscopical and
rcquirc for theİr identification histogical methods of examination.
Lesions are most promincnt in the brain stern, especially in the
medulla but are also present in all other parts of thG brain, such
as the midbrain, thalamus, hypothalamus, paraterminal body and
the cerebellum The spinal cord is also arkcted in a proportion
of nature! cases, but no lesions are found as a rule in the cerebral
haemispheres, cortex, hippocampus and amygdala (Zlotnik, 1957,
1958 I, 2 1960 and Zlotnik and Katiyar, 1961)}, number={03.04}, publisher={Ankara University}