@article{article_834435, title={Epidemiological and Biochemical Evaluation of Patients Under Monitoring with A Diagnosis of Crimean-Congo Hemorrhagic Fever}, journal={Journal of Biotechnology and Strategic Health Research}, volume={4}, pages={320–327}, year={2020}, DOI={10.34084/bshr.834435}, author={Parlak, Emine and Kesmez Can, Fatma and Alay, Handan and Parlak, Mehmet and Özkurt, Zülal and Koşan, Zahide}, keywords={Crimean-Congo Hemorrhagic Fever, mortality rate, Turkey}, abstract={Aim: Crimean-Congo Hemorrhagic Fever (CCHF) is a viral hemorrhagic fever. To evaluate the clinical, epidemiological and laboratory characteristics of patients with CCHF. Methods: This study was performed with adult patients under monitoring with diagnosis of CCHF at the Atatürk University Faculty of Medicine Infectious Diseases Clinic between April 2012 and August 2013. Results: Diagnosis of CCHF was based on presence of Enzyme-linked immunosorbent assay (ELISA) anti-CCFV IgM and/or virus antigen at Refik Saydam Hygiene Center (RSHM) in patient serum and/or real time Polymerase Chain Reaction (PCR). One hundred twenty-one cases were included. Fifty-eight (48.7%) of patients were male and 62(51.2%) female, with a mean age of 50.04 ± 18.22 (16-86) years. Contact with ticks was determined in 62.8% of patients. Length of incubation was 3.9±2.7 days. Five patients (4.1%) died. Conclusion: CCHF which is carried by ticks is a fatal viral infection. The most important factor in protection is the prevention of tick contact. People living in endemic regions must be educated and instructed how to perform daily tick checks. Patients have got high fever, myalgia, headache and tick bite must be asked in history. We believe that early diagnosis and treatment of CCHF cases may significantly reduce morbidity and mortality.}, number={3}, publisher={Deneysel, Biyoteknolojik, Klinik ve Stratejik Sağlık Araştırmaları Derneği}