@article{article_855842, title={A Duodenal Villous Adenoma Associated with Intramucosal Carcinoma}, journal={Tıp Fakültesi Klinikleri Dergisi}, volume={3}, pages={99–102}, year={2020}, author={Perek, Asiye and Ergun, Sefa and Durgun, Ali Vedat}, keywords={Duodenum neoplasms, Villous adenoma, Local excision}, abstract={Primary tumors of the small intestine are uncommon. There is an increase in the frequency
of villous and tubulovillous adenomas of the duodenum. This is likely to be caused by an
increase in application of endoscopic examination for evaluating gastrointestinal complaints
and for screening examination of patients with polyposis syndromes. Most frequently seen
benign periampullary neoplasm is duodenum villous adenomas. As they have a 30-60% rate of
malignant transformation, they are as considered to be premalignant lesions. They are usually
located near the ampulla of Vater and cause symptoms such as biliary obstruction, pancreatitis,
bleeding, duodenal obstruction. Pancreaticoduodenectomy remains the procedure of choice with
invasive cancer. The appropriate treatment for those lesions that are benign or contain carcinoma
in situ remains controversial. In these case we report a 69-year old woman, that the lesion is seen
incidentaly while placing a percutaneous endoscopic gastrostomy due to swallowing disorder
after cerebral operation. An endoscopic biopsy and pathological workup after local excision
revealed high diferantiated intramucosal adenocarcinoma.}, number={2}, publisher={Istanbul Aydin University}