TY - JOUR T1 - Çocuklarda Anafilaksi: Nedir? Ne Değildir? AU - Arga, Mustafa AU - Topal, Erdem PY - 2020 DA - April JF - Klinik Tıp Pediatri Dergisi JO - Pediatri PB - Selen Medya Yayıncılık Tanıtım ve Organizasyon Hizmetleri WT - DergiPark SN - 1309-0453 SP - 103 EP - 113 VL - 12 IS - 2 LA - tr AB - Anafilaksi yaşamı tehdit eden ve ölümle sonuçlanabilen ani başlangıçlı sistemikaşırı duyarlılık reaksiyonudur. Anafilaksi sıklığı son yirmi yılda tüm dünya genelindeönemli oranda artmıştır. Anafilaksi klinik bir tanı olmasına rağmen ortaya çıkanhiçbir belirti ve bulgu anafilaksiye özgün değildir. Aynı zamanda akut dönemde tanıyıdoğrulayabilecek ve rutin pratikte kullanılabilecek altın standart bir laboratuvartestte yoktur. Geliştirilmiş klinik tanı kriterleri tanısal sorunların çözümüne önemlioranda katkıda bulunmuş olsa da halen klinik pratikte birçok olgunun tanısı atlanabilmektedir.Anafilaksi tedavisi acil bir durumdur ve tek hayat kurtarıcı tedavi adrenalindir.Anafilaksiye bağlı ölümler için bilinen en önemli neden adrenalinin uygulanmamasıya da geç uygulanmasıdır. Bu nedenle anafilaksi tanı kriterlerini karşılayanher hastada adrenalin vakit kaybedilmeden uygulanmalıdır. Antihistaminlerve kortikosteroidler hiçbir zaman adrenalin yerine kullanılmamalıdır. Mutlaka herhastanın bir izlem süresi olmalıdır. Taburcu edilmeden önce hasta ve/veya ebeveynleretetikleyicilerden kaçınma/korunma yöntemleri anlatılmalı, acil durum hazırlığıtamamlanmalı ve uzun süreli izlem için alerji kliniklerine konsülte edilmelidir. KW - anafilaksi KW - adrenalin KW - çocuk KW - tanı KW - tedavi CR - 1. Orhan F, Civelek E, Sahiner UM, Arga M, Can D, Çalışkaner AZ, et al. Anaphylaxis: Turkish National Guideline 2018. 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