TY  - JOUR
T1  - Microwave-Assisted Synthesis and Characterization of Poly 1-Azabicyclo[4.2.0]octane  and Its Water-Soluble Derivatives
AU  - Karabulut, Erdem
AU  - Özdemir, Zafer Ömer
AU  - Yolaçan, Çiğdem
AU  - Sarıçay, Yunus
AU  - Mustafaeva, Zeynep
PY  - 2008
DA  - December
JF  - Hacettepe Journal of Biology and Chemistry
JO  - HJBC
PB  - Hacettepe University
WT  - DergiPark
SN  - 2687-475X
SP  - 319
EP  - 328
VL  - 36
IS  - 4
LA  - en
AB  - In this study we offer a new method to synthesize positively charged poly 1-Azabicyclo[4.2.0]octane -common nameis polyconidine- and its water-soluble polyampholyte derivative synthesized with bromoacetic acid using microwaveirradiation as a model carrier system for biological macromolecules like peptides, proteins and etc   1-Azabicyclo[4.2.0]octane containing unsubstituted four-membered azetidine ring was synthesized using microwaveassisted synthesis method and used as monomer in cationic ring-opening polymerization. Different alkyl halide  derivatives were used as initiators to start polymerization. Microwave-assisted synthesis of polyconidine derivatives  was carried out by bromoacetic acid using microwave irradiation. Characterization of polyconidine and its derivatives  was achieved by size-exclusion chromatography  SEC  with on line quadruple detection system, ATR FT-IR and UV  Spectroscopy
KW  - Polyconidine
KW  - microwave-assisted polymer synthesis
KW  - cationic ring-opening polymerization
CR  - 1. Lavagnino, E. R., Chauvette, R. R., Cannon, W. N., Kornfield, E. C., Conidine-synthesis, polymerization and derivatives, J. Amer. Chem. Soc. 82, 2609, 1960.
CR  - 2. Schulz, R.C., Schmidt, M., Schwarzenbach, E., Zöller, J., Some new polyelectrolytes, Macromol. Chem., Macromol. Symp. 26, 221- 231, 1989.
CR  - 3. Zaikov, G.E., Livshits V.S., Biodegradable polymers for medical purposes, Khim.-farm. Zh., No. 4, 416-427, 1984.
CR  - 4. Penczek, S., Cypryk, M., Duda, A., Kubisa, P., Slomkawski, S., Living ring-opening polymerizations of heterocyclic monomers, Prog. Polym. Sci. 32, 247, 2007.
CR  - 5. Mühlbach, K., Schulz, R.C., Polymers of 1- Azabicyclooctane[4.2.0]. Part 3. Modification of polystyrene-block-poly-1- azabicyclooctane[4.2.0], Acta Polymer. 46, 130-133, 1995.
CR  - 6. Nekrasov, A. V., Berestetskaya, T. Z., Kinetics and mechanism of copolymerization of conidine and β-propiolactone, Polymer Science U.S.S.R. 26, 1165, 1984.
CR  - 7. Mühlbach, K., Schulz, R.C., Polymers of 1- azabicyclo[4.2.0]octane, 1, Structure of monomer and homopolymer, Makromol. Chem. 189, 1267, 1988.
CR  - 8. Matyjaszewski, K., Cationic polymerization of 1-azabicyclo[4.2.0]octane 1, Alkylation, Makromol. Chem. 185, 37-49, 1984.
CR  - 9. Kropachev, V. A., Polymerization of heterocycles related to biomedical polymers, Pure and Applied Chem., 48, 355-361, 1976.
CR  - 10. Matyjaszewski, K., Szymanski, R., Kubisa, P., Penczek, ST., Ionic and covalent species in the cationic polymerization- equilibria and reactivities, Acta Polymer. 35, Nr. 1, 14, 1984.
CR  - 11. Topuzoğulları, M., Çimen, N.S., Mustafaeva, Z., Mustafaev, M., Molecular-weight distribution and structural transformation in water-soluble complexes of poly(acrylic acid) and bovine serum albumine, Eur. Poly. Jour., 43, 2935- 2946, 2007.
CR  - 12. Matyjaszewski, K. (Ed), Cationic Polymerizations: mechanisms, synthesis and applications, Marcel Dekker, Inc., 1996.
CR  - 13. Mustafaev M.I., Mustafaeva Z., Bermek E., Osada Y., New amphiphilic immunogens by Cu2+-mediated complexes of water-born poly(N-isopropylacrylamide) and bovine serum albumin, J. Bioact. Compat. Polymers 13, 33- 49, 1998.
UR  - https://dergipark.org.tr/en/pub/hjbc/issue//925939
L1  - https://dergipark.org.tr/en/download/article-file/1727560
ER  -