TY - JOUR T1 - The Chemistry of Formazans and Tetrazolium Salts TT - Formazanlar ve Tetrazolyum Tuzlarının Kimyası AU - Şenöz, Hülya PY - 2012 DA - August JF - Hacettepe Journal of Biology and Chemistry JO - HJBC PB - Hacettepe University WT - DergiPark SN - 2687-475X SP - 293 EP - 301 VL - 40 IS - 3 LA - en AB - In this rewiev, the structure of formazans and of tetrazolium salts has been described. Furthermore, importance and usage of formazan-tetrazolyum systems have been explained. Tautomerization properties and geometric isomers based on conjugate π-system of formazans have been examined. In addition, common synthesis of these compounds and UV-visible, IR, 1H NMR spectrums used in explanation of structures have been discussed. KW - Formazan KW - Tetrazolium salts KW - Tautomerization KW - Chelate form N2 - B u çalışmada tetrazolyum tuzları veformazanların yapıları tanımlanmıştır. Ayrıca formazan-tetrazolyum sistemlerinin önemi ve kullanım alanları açıklanmıştır. Formazanların sahip oldukları conjugate p-system kaynaklanan tautomerleşme özellikleri ve geometrik izomerleri incelenmiştir. Bu bileşiklerin en yaygın kullanılan sentezleri ve yapılarının açıklanmasında önemli olan UV-visible, IR ve 1H NMR spektrumları tartışılmıştır CR - 1. HV. Pechmann, P. Runge, Oxidation der Formazylverbindungen II, Ber. Deutsch. Chem. Ges. 27 (1894) 2920. CR - 2. GH. Findlay, The value of some tetrazolium salts as histochemical reagents for sulphydryl groups, J. Histochem. Cytochem. 3 (1955) 331. CR - 3. E. Koren, R. Kohen, I. Gınsburg, A CobaltBased Tetrazolium Salts Reduction Test to Assay Polyphenols J. Agric. Food Chem., 57 (2009) 7644. CR - 4. E. Seidler, The tetrazolium- Formazan System, Prog. in Histochem. and Cytochem. 24 (1991) 1. CR - 5. R. Kuhn, D. Jerchel, Reduktion von Tetrazoliumsalzen durch Bakterier garende Hefe und keimende Samen., Ber. Deutsch. Chem. Ges. 74 (1941) 949. CR - 6. AN Babu, RR. 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